Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species

The role of reactive oxygen species (ROS) in signalling and specific targets is not fully understood. Here the authors perform a global proteomic analysis to delineate the yeast redoxome and show that increased levels of intracellular ROS caused by dysfunctional mitochondria decrease global protein...

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Autores principales: Ulrike Topf, Ida Suppanz, Lukasz Samluk, Lidia Wrobel, Alexander Böser, Paulina Sakowska, Bettina Knapp, Martyna K. Pietrzyk, Agnieszka Chacinska, Bettina Warscheid
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/dbae8e44a79e41df9b1f9b615b6f8901
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