Spindle power is not affected after spontaneous K-complexes during human NREM sleep.

K-complexes and sleep spindles often grouped together characterize the second stage of NREM sleep and interest has been raised on a possible interaction of their underlying mechanisms. The reported inhibition of spindles power for about 15 seconds following evoked K-complexes has implications on the...

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Autores principales:	Andreas M Koupparis, Vasileios Kokkinos, George K Kostopoulos
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/dbb36d877f6d4b86af4a43f3cf44aa8c
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spelling	oai:doaj.org-article:dbb36d877f6d4b86af4a43f3cf44aa8c2021-11-18T08:01:56ZSpindle power is not affected after spontaneous K-complexes during human NREM sleep.1932-620310.1371/journal.pone.0054343https://doaj.org/article/dbb36d877f6d4b86af4a43f3cf44aa8c2013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326604/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203K-complexes and sleep spindles often grouped together characterize the second stage of NREM sleep and interest has been raised on a possible interaction of their underlying mechanisms. The reported inhibition of spindles power for about 15 seconds following evoked K-complexes has implications on their role in arousal. Our objective was to assess this inhibition following spontaneous K-complexes. We used time-frequency analysis of spontaneous K-complexes selected from whole-night EEG recordings of normal subjects. Our results show that spindles are most often observed at the positive phase following the peak of a spontaneous KC (70%). At latencies of 1-3 s following the peak of the K-complex, spindles almost disappear. Compared to long-term effects described for evoked KCs, sleep spindle power is not affected by spontaneous KCs for latencies of 5-15 s. Observation of the recurrence rate of sporadic spindles suggests that the reduction of power at 1-3 s most likely reflects a refractory period of spindles lasting for 1-2 s, rather than an effect of KCs. These results suggest that the mechanisms underlying spontaneous KCs do not affect spindle power as in the case of evoked KCs.Andreas M KoupparisVasileios KokkinosGeorge K KostopoulosPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 1, p e54343 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Andreas M Koupparis Vasileios Kokkinos George K Kostopoulos Spindle power is not affected after spontaneous K-complexes during human NREM sleep.
description	K-complexes and sleep spindles often grouped together characterize the second stage of NREM sleep and interest has been raised on a possible interaction of their underlying mechanisms. The reported inhibition of spindles power for about 15 seconds following evoked K-complexes has implications on their role in arousal. Our objective was to assess this inhibition following spontaneous K-complexes. We used time-frequency analysis of spontaneous K-complexes selected from whole-night EEG recordings of normal subjects. Our results show that spindles are most often observed at the positive phase following the peak of a spontaneous KC (70%). At latencies of 1-3 s following the peak of the K-complex, spindles almost disappear. Compared to long-term effects described for evoked KCs, sleep spindle power is not affected by spontaneous KCs for latencies of 5-15 s. Observation of the recurrence rate of sporadic spindles suggests that the reduction of power at 1-3 s most likely reflects a refractory period of spindles lasting for 1-2 s, rather than an effect of KCs. These results suggest that the mechanisms underlying spontaneous KCs do not affect spindle power as in the case of evoked KCs.
format	article
author	Andreas M Koupparis Vasileios Kokkinos George K Kostopoulos
author_facet	Andreas M Koupparis Vasileios Kokkinos George K Kostopoulos
author_sort	Andreas M Koupparis
title	Spindle power is not affected after spontaneous K-complexes during human NREM sleep.
title_short	Spindle power is not affected after spontaneous K-complexes during human NREM sleep.
title_full	Spindle power is not affected after spontaneous K-complexes during human NREM sleep.
title_fullStr	Spindle power is not affected after spontaneous K-complexes during human NREM sleep.
title_full_unstemmed	Spindle power is not affected after spontaneous K-complexes during human NREM sleep.
title_sort	spindle power is not affected after spontaneous k-complexes during human nrem sleep.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/dbb36d877f6d4b86af4a43f3cf44aa8c
work_keys_str_mv	AT andreasmkoupparis spindlepowerisnotaffectedafterspontaneouskcomplexesduringhumannremsleep AT vasileioskokkinos spindlepowerisnotaffectedafterspontaneouskcomplexesduringhumannremsleep AT georgekkostopoulos spindlepowerisnotaffectedafterspontaneouskcomplexesduringhumannremsleep
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Spindle power is not affected after spontaneous K-complexes during human NREM sleep.

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