Terminator-free template-independent enzymatic DNA synthesis for digital information storage

Adoption of DNA as a data storage medium could be accelerated with specialized synthesis processes and codecs. The authors describe TdT-mediated DNA synthesis in which data is stored in transitions between non-identical nucleotides and the use of synchronization markers to provide error tolerance.

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Autores principales:	Henry H. Lee, Reza Kalhor, Naveen Goela, Jean Bolot, George M. Church
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dbba1ab593104571a6b337fe731ad32e
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spelling	oai:doaj.org-article:dbba1ab593104571a6b337fe731ad32e2021-12-02T16:57:25ZTerminator-free template-independent enzymatic DNA synthesis for digital information storage10.1038/s41467-019-10258-12041-1723https://doaj.org/article/dbba1ab593104571a6b337fe731ad32e2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10258-1https://doaj.org/toc/2041-1723Adoption of DNA as a data storage medium could be accelerated with specialized synthesis processes and codecs. The authors describe TdT-mediated DNA synthesis in which data is stored in transitions between non-identical nucleotides and the use of synchronization markers to provide error tolerance.Henry H. LeeReza KalhorNaveen GoelaJean BolotGeorge M. ChurchNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Henry H. Lee Reza Kalhor Naveen Goela Jean Bolot George M. Church Terminator-free template-independent enzymatic DNA synthesis for digital information storage
description	Adoption of DNA as a data storage medium could be accelerated with specialized synthesis processes and codecs. The authors describe TdT-mediated DNA synthesis in which data is stored in transitions between non-identical nucleotides and the use of synchronization markers to provide error tolerance.
format	article
author	Henry H. Lee Reza Kalhor Naveen Goela Jean Bolot George M. Church
author_facet	Henry H. Lee Reza Kalhor Naveen Goela Jean Bolot George M. Church
author_sort	Henry H. Lee
title	Terminator-free template-independent enzymatic DNA synthesis for digital information storage
title_short	Terminator-free template-independent enzymatic DNA synthesis for digital information storage
title_full	Terminator-free template-independent enzymatic DNA synthesis for digital information storage
title_fullStr	Terminator-free template-independent enzymatic DNA synthesis for digital information storage
title_full_unstemmed	Terminator-free template-independent enzymatic DNA synthesis for digital information storage
title_sort	terminator-free template-independent enzymatic dna synthesis for digital information storage
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/dbba1ab593104571a6b337fe731ad32e
work_keys_str_mv	AT henryhlee terminatorfreetemplateindependentenzymaticdnasynthesisfordigitalinformationstorage AT rezakalhor terminatorfreetemplateindependentenzymaticdnasynthesisfordigitalinformationstorage AT naveengoela terminatorfreetemplateindependentenzymaticdnasynthesisfordigitalinformationstorage AT jeanbolot terminatorfreetemplateindependentenzymaticdnasynthesisfordigitalinformationstorage AT georgemchurch terminatorfreetemplateindependentenzymaticdnasynthesisfordigitalinformationstorage
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Terminator-free template-independent enzymatic DNA synthesis for digital information storage

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