FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora

Circadian clocks control daily rhythms of molecular and physiological activities. Here, the authors show that the interaction between proteins FRQ and CK1, rather than FRQ stability, is a major rate-limiting step in circadian period determination in the model fungus Neurospora.

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Autores principales: Xiao Liu, Ahai Chen, Angélica Caicedo-Casso, Guofei Cui, Mingjian Du, Qun He, Sookkyung Lim, Hang J. Kim, Christian I. Hong, Yi Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/dbbfd0b2ae6044ad9025f01804098213
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spelling oai:doaj.org-article:dbbfd0b2ae6044ad9025f018040982132021-12-02T14:40:00ZFRQ-CK1 interaction determines the period of circadian rhythms in Neurospora10.1038/s41467-019-12239-w2041-1723https://doaj.org/article/dbbfd0b2ae6044ad9025f018040982132019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12239-whttps://doaj.org/toc/2041-1723Circadian clocks control daily rhythms of molecular and physiological activities. Here, the authors show that the interaction between proteins FRQ and CK1, rather than FRQ stability, is a major rate-limiting step in circadian period determination in the model fungus Neurospora.Xiao LiuAhai ChenAngélica Caicedo-CassoGuofei CuiMingjian DuQun HeSookkyung LimHang J. KimChristian I. HongYi LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiao Liu
Ahai Chen
Angélica Caicedo-Casso
Guofei Cui
Mingjian Du
Qun He
Sookkyung Lim
Hang J. Kim
Christian I. Hong
Yi Liu
FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
description Circadian clocks control daily rhythms of molecular and physiological activities. Here, the authors show that the interaction between proteins FRQ and CK1, rather than FRQ stability, is a major rate-limiting step in circadian period determination in the model fungus Neurospora.
format article
author Xiao Liu
Ahai Chen
Angélica Caicedo-Casso
Guofei Cui
Mingjian Du
Qun He
Sookkyung Lim
Hang J. Kim
Christian I. Hong
Yi Liu
author_facet Xiao Liu
Ahai Chen
Angélica Caicedo-Casso
Guofei Cui
Mingjian Du
Qun He
Sookkyung Lim
Hang J. Kim
Christian I. Hong
Yi Liu
author_sort Xiao Liu
title FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
title_short FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
title_full FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
title_fullStr FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
title_full_unstemmed FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
title_sort frq-ck1 interaction determines the period of circadian rhythms in neurospora
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/dbbfd0b2ae6044ad9025f01804098213
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