FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
Circadian clocks control daily rhythms of molecular and physiological activities. Here, the authors show that the interaction between proteins FRQ and CK1, rather than FRQ stability, is a major rate-limiting step in circadian period determination in the model fungus Neurospora.
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Nature Portfolio
2019
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oai:doaj.org-article:dbbfd0b2ae6044ad9025f018040982132021-12-02T14:40:00ZFRQ-CK1 interaction determines the period of circadian rhythms in Neurospora10.1038/s41467-019-12239-w2041-1723https://doaj.org/article/dbbfd0b2ae6044ad9025f018040982132019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12239-whttps://doaj.org/toc/2041-1723Circadian clocks control daily rhythms of molecular and physiological activities. Here, the authors show that the interaction between proteins FRQ and CK1, rather than FRQ stability, is a major rate-limiting step in circadian period determination in the model fungus Neurospora.Xiao LiuAhai ChenAngélica Caicedo-CassoGuofei CuiMingjian DuQun HeSookkyung LimHang J. KimChristian I. HongYi LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Xiao Liu Ahai Chen Angélica Caicedo-Casso Guofei Cui Mingjian Du Qun He Sookkyung Lim Hang J. Kim Christian I. Hong Yi Liu FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora |
description |
Circadian clocks control daily rhythms of molecular and physiological activities. Here, the authors show that the interaction between proteins FRQ and CK1, rather than FRQ stability, is a major rate-limiting step in circadian period determination in the model fungus Neurospora. |
format |
article |
author |
Xiao Liu Ahai Chen Angélica Caicedo-Casso Guofei Cui Mingjian Du Qun He Sookkyung Lim Hang J. Kim Christian I. Hong Yi Liu |
author_facet |
Xiao Liu Ahai Chen Angélica Caicedo-Casso Guofei Cui Mingjian Du Qun He Sookkyung Lim Hang J. Kim Christian I. Hong Yi Liu |
author_sort |
Xiao Liu |
title |
FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora |
title_short |
FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora |
title_full |
FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora |
title_fullStr |
FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora |
title_full_unstemmed |
FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora |
title_sort |
frq-ck1 interaction determines the period of circadian rhythms in neurospora |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/dbbfd0b2ae6044ad9025f01804098213 |
work_keys_str_mv |
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1718390446813609984 |