Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency.
Despite the effectiveness of highly active antiretroviral therapy (HAART) in treating individuals infected with HIV, HAART is not a cure. A latent reservoir, composed mainly of resting CD4+T cells, drives viral rebound once therapy is stopped. Understanding the formation and maintenance of latently...
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| Auteurs principaux: | , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2012
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| Accès en ligne: | https://doaj.org/article/dbccde35766d4ad09774f366e3f2ac9f |
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