Inhibition of MMP2-PEX by a novel ester of dihydroxy cinnamic and linoleic acid from the seagrass Cymodocea serrulata

Abstract Matrix metalloproteinases (MMPs) are pivotal for cancer cell migration and metastasis which are generally over-expressed in such cell types. Many drugs targeting MMPs do so by binding to the conserved catalytic domains and thus exhibit poor selectivity due to domain-similarities with other...

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Auteurs principaux: V. S. Christina, R. Lakshmi Sundaram, V. Sivamurugan, D. Thirumal Kumar, C. D. Mohanapriya, V. L. Shailaja, S. P. Thyagarajan, C. George Priya Doss, K. Mary Elizabeth Gnanambal
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/dbcf18e089ee464eabd1034aab9e7cd4
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