Late p65 nuclear translocation in glioblastoma cells indicates non-canonical TLR4 signaling and activation of DNA repair genes

Abstract Glioblastoma (GBM) is the most aggressive brain primary malignancy. Toll-like receptor 4 (TLR4) has a dual role in cell fate, promoting cell survival or death depending on the context. Here, we analyzed TLR4 expression in different grades of astrocytoma, and observed increased expression in...

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Autores principales: Isabele F. Moretti, Antonio M. Lerario, Marina Trombetta-Lima, Paula R. Sola, Roseli da Silva Soares, Sueli M. Oba-Shinjo, Suely K. N. Marie
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/dbd539efc27248eda907583955f9ce84
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