Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure

Fever is a defence mechanism against infection, but it may also cause abnormal heart rhythm viaunknown mechanism. Here the authors identify FHF2 protein as a key regulator of myocardial excitability that protects the heart against conduction failure in response to an increase in body temperature.

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Autores principales:	David S. Park, Akshay Shekhar, Christopher Marra, Xianming Lin, Carolina Vasquez, Sergio Solinas, Kevin Kelley, Gregory Morley, Mitchell Goldfarb, Glenn I. Fishman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dbdb59efebce4638830ecefe86c9f954
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spelling	oai:doaj.org-article:dbdb59efebce4638830ecefe86c9f9542021-12-02T15:34:30ZFhf2 gene deletion causes temperature-sensitive cardiac conduction failure10.1038/ncomms129662041-1723https://doaj.org/article/dbdb59efebce4638830ecefe86c9f9542016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12966https://doaj.org/toc/2041-1723Fever is a defence mechanism against infection, but it may also cause abnormal heart rhythm viaunknown mechanism. Here the authors identify FHF2 protein as a key regulator of myocardial excitability that protects the heart against conduction failure in response to an increase in body temperature.David S. ParkAkshay ShekharChristopher MarraXianming LinCarolina VasquezSergio SolinasKevin KelleyGregory MorleyMitchell GoldfarbGlenn I. FishmanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David S. Park Akshay Shekhar Christopher Marra Xianming Lin Carolina Vasquez Sergio Solinas Kevin Kelley Gregory Morley Mitchell Goldfarb Glenn I. Fishman Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure
description	Fever is a defence mechanism against infection, but it may also cause abnormal heart rhythm viaunknown mechanism. Here the authors identify FHF2 protein as a key regulator of myocardial excitability that protects the heart against conduction failure in response to an increase in body temperature.
format	article
author	David S. Park Akshay Shekhar Christopher Marra Xianming Lin Carolina Vasquez Sergio Solinas Kevin Kelley Gregory Morley Mitchell Goldfarb Glenn I. Fishman
author_facet	David S. Park Akshay Shekhar Christopher Marra Xianming Lin Carolina Vasquez Sergio Solinas Kevin Kelley Gregory Morley Mitchell Goldfarb Glenn I. Fishman
author_sort	David S. Park
title	Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure
title_short	Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure
title_full	Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure
title_fullStr	Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure
title_full_unstemmed	Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure
title_sort	fhf2 gene deletion causes temperature-sensitive cardiac conduction failure
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/dbdb59efebce4638830ecefe86c9f954
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Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure

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