Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis.

Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis.

The neurosteroid dehydroepiandrosterone (DHEA), produced by neurons and glia, affects multiple processes in the brain, including neuronal survival and neurogenesis during development and in aging. We provide evidence that DHEA interacts with pro-survival TrkA and pro-death p75(NTR) membrane receptor...

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Autores principales: Iakovos Lazaridis, Ioannis Charalampopoulos, Vassilia-Ismini Alexaki, Nicolaos Avlonitis, Iosif Pediaditakis, Paschalis Efstathopoulos, Theodora Calogeropoulou, Elias Castanas, Achille Gravanis
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/dbe163e54a0e4535ad2d6f966129287a
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