Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction

In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues.

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Detalles Bibliográficos
Autores principales: Rongfeng Zhu, Gong Zhang, Miao Jing, Yu Han, Jiaofeng Li, Jingyi Zhao, Yulong Li, Peng R. Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/dbe7042aba324d82aee7aceb94e4d65b
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Sumario:In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues.