Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues.
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Nature Portfolio
2021
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oai:doaj.org-article:dbe7042aba324d82aee7aceb94e4d65b2021-12-02T14:16:13ZGenetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction10.1038/s41467-020-20754-42041-1723https://doaj.org/article/dbe7042aba324d82aee7aceb94e4d65b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20754-4https://doaj.org/toc/2041-1723In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues.Rongfeng ZhuGong ZhangMiao JingYu HanJiaofeng LiJingyi ZhaoYulong LiPeng R. ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Rongfeng Zhu Gong Zhang Miao Jing Yu Han Jiaofeng Li Jingyi Zhao Yulong Li Peng R. Chen Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction |
description |
In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues. |
format |
article |
author |
Rongfeng Zhu Gong Zhang Miao Jing Yu Han Jiaofeng Li Jingyi Zhao Yulong Li Peng R. Chen |
author_facet |
Rongfeng Zhu Gong Zhang Miao Jing Yu Han Jiaofeng Li Jingyi Zhao Yulong Li Peng R. Chen |
author_sort |
Rongfeng Zhu |
title |
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction |
title_short |
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction |
title_full |
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction |
title_fullStr |
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction |
title_full_unstemmed |
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction |
title_sort |
genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/dbe7042aba324d82aee7aceb94e4d65b |
work_keys_str_mv |
AT rongfengzhu geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction AT gongzhang geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction AT miaojing geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction AT yuhan geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction AT jiaofengli geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction AT jingyizhao geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction AT yulongli geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction AT pengrchen geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction |
_version_ |
1718391754256809984 |