Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction

In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues.

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Autores principales: Rongfeng Zhu, Gong Zhang, Miao Jing, Yu Han, Jiaofeng Li, Jingyi Zhao, Yulong Li, Peng R. Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/dbe7042aba324d82aee7aceb94e4d65b
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spelling oai:doaj.org-article:dbe7042aba324d82aee7aceb94e4d65b2021-12-02T14:16:13ZGenetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction10.1038/s41467-020-20754-42041-1723https://doaj.org/article/dbe7042aba324d82aee7aceb94e4d65b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20754-4https://doaj.org/toc/2041-1723In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues.Rongfeng ZhuGong ZhangMiao JingYu HanJiaofeng LiJingyi ZhaoYulong LiPeng R. ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rongfeng Zhu
Gong Zhang
Miao Jing
Yu Han
Jiaofeng Li
Jingyi Zhao
Yulong Li
Peng R. Chen
Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
description In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues.
format article
author Rongfeng Zhu
Gong Zhang
Miao Jing
Yu Han
Jiaofeng Li
Jingyi Zhao
Yulong Li
Peng R. Chen
author_facet Rongfeng Zhu
Gong Zhang
Miao Jing
Yu Han
Jiaofeng Li
Jingyi Zhao
Yulong Li
Peng R. Chen
author_sort Rongfeng Zhu
title Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
title_short Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
title_full Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
title_fullStr Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
title_full_unstemmed Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
title_sort genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/dbe7042aba324d82aee7aceb94e4d65b
work_keys_str_mv AT rongfengzhu geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction
AT gongzhang geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction
AT miaojing geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction
AT yuhan geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction
AT jiaofengli geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction
AT jingyizhao geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction
AT yulongli geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction
AT pengrchen geneticallyencodedformaldehydesensorsinspiredbyaproteinintrahelicalcrosslinkingreaction
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