Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway

H3K36 methylation by Set2 targets Rpd3S histone deacetylase to transcribed mRNA genes, repressing internal cryptic promoters and modulating elongation. Here, the authors provide evidence that the Set2-Rpd3S pathway also regulates dynamic expression of mRNAs and lncRNAs.

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Autores principales:	Ji Hyun Kim, Bo Bae Lee, Young Mi Oh, Chenchen Zhu, Lars M. Steinmetz, Yookyeong Lee, Wan Kyu Kim, Sung Bae Lee, Stephen Buratowski, TaeSoo Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dbf3891b60f2429294504f03df887f75
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spelling	oai:doaj.org-article:dbf3891b60f2429294504f03df887f752021-12-02T17:32:50ZModulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway10.1038/ncomms135342041-1723https://doaj.org/article/dbf3891b60f2429294504f03df887f752016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13534https://doaj.org/toc/2041-1723H3K36 methylation by Set2 targets Rpd3S histone deacetylase to transcribed mRNA genes, repressing internal cryptic promoters and modulating elongation. Here, the authors provide evidence that the Set2-Rpd3S pathway also regulates dynamic expression of mRNAs and lncRNAs.Ji Hyun KimBo Bae LeeYoung Mi OhChenchen ZhuLars M. SteinmetzYookyeong LeeWan Kyu KimSung Bae LeeStephen BuratowskiTaeSoo KimNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ji Hyun Kim Bo Bae Lee Young Mi Oh Chenchen Zhu Lars M. Steinmetz Yookyeong Lee Wan Kyu Kim Sung Bae Lee Stephen Buratowski TaeSoo Kim Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway
description	H3K36 methylation by Set2 targets Rpd3S histone deacetylase to transcribed mRNA genes, repressing internal cryptic promoters and modulating elongation. Here, the authors provide evidence that the Set2-Rpd3S pathway also regulates dynamic expression of mRNAs and lncRNAs.
format	article
author	Ji Hyun Kim Bo Bae Lee Young Mi Oh Chenchen Zhu Lars M. Steinmetz Yookyeong Lee Wan Kyu Kim Sung Bae Lee Stephen Buratowski TaeSoo Kim
author_facet	Ji Hyun Kim Bo Bae Lee Young Mi Oh Chenchen Zhu Lars M. Steinmetz Yookyeong Lee Wan Kyu Kim Sung Bae Lee Stephen Buratowski TaeSoo Kim
author_sort	Ji Hyun Kim
title	Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway
title_short	Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway
title_full	Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway
title_fullStr	Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway
title_full_unstemmed	Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway
title_sort	modulation of mrna and lncrna expression dynamics by the set2–rpd3s pathway
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/dbf3891b60f2429294504f03df887f75
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Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway

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