Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling
Abstract Conformational activation of integrins is generally required for ligand binding and cellular signalling. However, we have previously reported that the nonactivated conformation of α2β1 integrin can also bind to large ligands, such as human echovirus 1. In this study, we show that the intera...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2017
|
| Subjects: | |
| Online Access: | https://doaj.org/article/dbf99cfe587e47e9a99e9658e71ebd1f |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|