Fatty acid ethyl esters induce intestinal epithelial barrier dysfunction via a reactive oxygen species-dependent mechanism in a three-dimensional cell culture model.

Fatty acid ethyl esters induce intestinal epithelial barrier dysfunction via a reactive oxygen species-dependent mechanism in a three-dimensional cell culture model.

<h4>Background & aims</h4>Evidence is accumulating that ethanol and its oxidative metabolite, acetaldehyde, can disrupt intestinal epithelial integrity, an important factor contributing to ethanol-induced liver injury. However, ethanol can also be metabolized non-oxidatively generati...

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Autores principales: Elhaseen Elamin, Ad Masclee, Kati Juuti-Uusitalo, Sven van Ijzendoorn, Freddy Troost, Harm-Jan Pieters, Jan Dekker, Daisy Jonkers
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/dbfaadaf204848309a5706096b30c17e
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