Not all partial dopamine D2 receptor agonists are the same in treating schizophrenia. Exploring the effects of bifeprunox and aripiprazole using a computer model of a primate striatal dopaminergic synapse
Athan Spiros1, Robert Carr1, Hugo Geerts1,21In Silico Biosciences, Berwyn, PA, USA; 2School of Medicine, University of Pennsylvania, PA, USAAbstract: Species differences in physiology and unique active human metabolites contribute to the limited predictive value of preclinical rodent models for many...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
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Dove Medical Press
2010
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| Accès en ligne: | https://doaj.org/article/dbfab43968d34192ba8f1f3adc8a528e |
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