Not all partial dopamine D2 receptor agonists are the same in treating schizophrenia. Exploring the effects of bifeprunox and aripiprazole using a computer model of a primate striatal dopaminergic synapse

Athan Spiros1, Robert Carr1, Hugo Geerts1,21In Silico Biosciences, Berwyn, PA, USA; 2School of Medicine, University of Pennsylvania, PA, USAAbstract: Species differences in physiology and unique active human metabolites contribute to the limited predictive value of preclinical rodent models for many...

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Bibliographic Details
Main Authors: Athan Spiros, Robert Carr, Hugo Geerts
Format: article
Language:EN
Published: Dove Medical Press 2010
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Online Access:https://doaj.org/article/dbfab43968d34192ba8f1f3adc8a528e
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