INFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES

Immunomodulating ability of a bacterial preparation (Immunovak VP-4 vaccine), and a compound of eukariotic origin (profetal), the main active component of human α-fetoprotein were under investigation in present study. Culturing of mononuclear leukocytes with the immunomodulatory factors promotes qua...

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Autores principales:	E. A. Lebedinskaya, N. K. Akhmatova, O. V. Lebedinskaya, V. A. Chereshnev, S. U. Rodionov, M. V. Kiselevsky
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	immunomodulators immunovak-vp-4 profetal natural killers cytotoxic activity immunophenotype Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/dbfd11bdad5843bcaff2651d2d51dabd
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spelling	oai:doaj.org-article:dbfd11bdad5843bcaff2651d2d51dabd2021-11-18T08:03:37ZINFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES1563-06252313-741X10.15789/1563-0625-2009-1-15-20https://doaj.org/article/dbfd11bdad5843bcaff2651d2d51dabd2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/36https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XImmunomodulating ability of a bacterial preparation (Immunovak VP-4 vaccine), and a compound of eukariotic origin (profetal), the main active component of human α-fetoprotein were under investigation in present study. Culturing of mononuclear leukocytes with the immunomodulatory factors promotes quantitative increase of the cells that express surface antigens specific for cytotoxic lymphocytes, natural killers and natural killer T-cells. Both bio-active preparations possess an expressed anti-cancer effect in vitro, i.e., they induce activation of killing properties of human peripheral blood mononuclear leukocytes, which is accompanied by acquiring their characteristic phenotype.E. A. LebedinskayaN. K. AkhmatovaO. V. LebedinskayaV. A. ChereshnevS. U. RodionovM. V. KiselevskySPb RAACIarticleimmunomodulatorsimmunovak-vp-4profetalnatural killerscytotoxic activityimmunophenotypeImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 1, Pp 15-20 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	immunomodulators immunovak-vp-4 profetal natural killers cytotoxic activity immunophenotype Immunologic diseases. Allergy RC581-607
spellingShingle	immunomodulators immunovak-vp-4 profetal natural killers cytotoxic activity immunophenotype Immunologic diseases. Allergy RC581-607 E. A. Lebedinskaya N. K. Akhmatova O. V. Lebedinskaya V. A. Chereshnev S. U. Rodionov M. V. Kiselevsky INFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES
description	Immunomodulating ability of a bacterial preparation (Immunovak VP-4 vaccine), and a compound of eukariotic origin (profetal), the main active component of human α-fetoprotein were under investigation in present study. Culturing of mononuclear leukocytes with the immunomodulatory factors promotes quantitative increase of the cells that express surface antigens specific for cytotoxic lymphocytes, natural killers and natural killer T-cells. Both bio-active preparations possess an expressed anti-cancer effect in vitro, i.e., they induce activation of killing properties of human peripheral blood mononuclear leukocytes, which is accompanied by acquiring their characteristic phenotype.
format	article
author	E. A. Lebedinskaya N. K. Akhmatova O. V. Lebedinskaya V. A. Chereshnev S. U. Rodionov M. V. Kiselevsky
author_facet	E. A. Lebedinskaya N. K. Akhmatova O. V. Lebedinskaya V. A. Chereshnev S. U. Rodionov M. V. Kiselevsky
author_sort	E. A. Lebedinskaya
title	INFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES
title_short	INFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES
title_full	INFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES
title_fullStr	INFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES
title_full_unstemmed	INFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES
title_sort	influence of immunomodulating agents immunovak vp-4 and profetal on functional activity of mononuclear leukocytes
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/dbfd11bdad5843bcaff2651d2d51dabd
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INFLUENCE OF IMMUNOMODULATING AGENTS IMMUNOVAK VP-4 AND PROFETAL ON FUNCTIONAL ACTIVITY OF MONONUCLEAR LEUKOCYTES

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