CHML promotes liver cancer metastasis by facilitating Rab14 recycle
Metastasis-associated recurrence is a major cause of poor prognosis in hepatocellular carcinoma. Here, the authors show that expression of choroideremia-like (CHML) is elevated and associates with poor prognosis in hepatocellular carcinoma, and mechanistically CHML promotes metastasis in a Rab14-dep...
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Nature Portfolio
2019
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oai:doaj.org-article:dc0b4bcc791f411d85b4e5b46c2d6ddb2021-12-02T15:35:55ZCHML promotes liver cancer metastasis by facilitating Rab14 recycle10.1038/s41467-019-10364-02041-1723https://doaj.org/article/dc0b4bcc791f411d85b4e5b46c2d6ddb2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10364-0https://doaj.org/toc/2041-1723Metastasis-associated recurrence is a major cause of poor prognosis in hepatocellular carcinoma. Here, the authors show that expression of choroideremia-like (CHML) is elevated and associates with poor prognosis in hepatocellular carcinoma, and mechanistically CHML promotes metastasis in a Rab14-dependent manner.Tian-Wei ChenFen-Fen YinYan-Mei YuanDong-Xian GuanErbin ZhangFeng-Kun ZhangHao JiangNing MaJing-Jing WangQian-Zhi NiLin QiuJing FengXue-Li ZhangYing BaoKang WangShu-Qun ChengXiao-Fan WangXiang WangJing-Jing LiDong XieNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Tian-Wei Chen Fen-Fen Yin Yan-Mei Yuan Dong-Xian Guan Erbin Zhang Feng-Kun Zhang Hao Jiang Ning Ma Jing-Jing Wang Qian-Zhi Ni Lin Qiu Jing Feng Xue-Li Zhang Ying Bao Kang Wang Shu-Qun Cheng Xiao-Fan Wang Xiang Wang Jing-Jing Li Dong Xie CHML promotes liver cancer metastasis by facilitating Rab14 recycle |
description |
Metastasis-associated recurrence is a major cause of poor prognosis in hepatocellular carcinoma. Here, the authors show that expression of choroideremia-like (CHML) is elevated and associates with poor prognosis in hepatocellular carcinoma, and mechanistically CHML promotes metastasis in a Rab14-dependent manner. |
format |
article |
author |
Tian-Wei Chen Fen-Fen Yin Yan-Mei Yuan Dong-Xian Guan Erbin Zhang Feng-Kun Zhang Hao Jiang Ning Ma Jing-Jing Wang Qian-Zhi Ni Lin Qiu Jing Feng Xue-Li Zhang Ying Bao Kang Wang Shu-Qun Cheng Xiao-Fan Wang Xiang Wang Jing-Jing Li Dong Xie |
author_facet |
Tian-Wei Chen Fen-Fen Yin Yan-Mei Yuan Dong-Xian Guan Erbin Zhang Feng-Kun Zhang Hao Jiang Ning Ma Jing-Jing Wang Qian-Zhi Ni Lin Qiu Jing Feng Xue-Li Zhang Ying Bao Kang Wang Shu-Qun Cheng Xiao-Fan Wang Xiang Wang Jing-Jing Li Dong Xie |
author_sort |
Tian-Wei Chen |
title |
CHML promotes liver cancer metastasis by facilitating Rab14 recycle |
title_short |
CHML promotes liver cancer metastasis by facilitating Rab14 recycle |
title_full |
CHML promotes liver cancer metastasis by facilitating Rab14 recycle |
title_fullStr |
CHML promotes liver cancer metastasis by facilitating Rab14 recycle |
title_full_unstemmed |
CHML promotes liver cancer metastasis by facilitating Rab14 recycle |
title_sort |
chml promotes liver cancer metastasis by facilitating rab14 recycle |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/dc0b4bcc791f411d85b4e5b46c2d6ddb |
work_keys_str_mv |
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