CHML promotes liver cancer metastasis by facilitating Rab14 recycle

Metastasis-associated recurrence is a major cause of poor prognosis in hepatocellular carcinoma. Here, the authors show that expression of choroideremia-like (CHML) is elevated and associates with poor prognosis in hepatocellular carcinoma, and mechanistically CHML promotes metastasis in a Rab14-dep...

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Autores principales: Tian-Wei Chen, Fen-Fen Yin, Yan-Mei Yuan, Dong-Xian Guan, Erbin Zhang, Feng-Kun Zhang, Hao Jiang, Ning Ma, Jing-Jing Wang, Qian-Zhi Ni, Lin Qiu, Jing Feng, Xue-Li Zhang, Ying Bao, Kang Wang, Shu-Qun Cheng, Xiao-Fan Wang, Xiang Wang, Jing-Jing Li, Dong Xie
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/dc0b4bcc791f411d85b4e5b46c2d6ddb
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spelling oai:doaj.org-article:dc0b4bcc791f411d85b4e5b46c2d6ddb2021-12-02T15:35:55ZCHML promotes liver cancer metastasis by facilitating Rab14 recycle10.1038/s41467-019-10364-02041-1723https://doaj.org/article/dc0b4bcc791f411d85b4e5b46c2d6ddb2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10364-0https://doaj.org/toc/2041-1723Metastasis-associated recurrence is a major cause of poor prognosis in hepatocellular carcinoma. Here, the authors show that expression of choroideremia-like (CHML) is elevated and associates with poor prognosis in hepatocellular carcinoma, and mechanistically CHML promotes metastasis in a Rab14-dependent manner.Tian-Wei ChenFen-Fen YinYan-Mei YuanDong-Xian GuanErbin ZhangFeng-Kun ZhangHao JiangNing MaJing-Jing WangQian-Zhi NiLin QiuJing FengXue-Li ZhangYing BaoKang WangShu-Qun ChengXiao-Fan WangXiang WangJing-Jing LiDong XieNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tian-Wei Chen
Fen-Fen Yin
Yan-Mei Yuan
Dong-Xian Guan
Erbin Zhang
Feng-Kun Zhang
Hao Jiang
Ning Ma
Jing-Jing Wang
Qian-Zhi Ni
Lin Qiu
Jing Feng
Xue-Li Zhang
Ying Bao
Kang Wang
Shu-Qun Cheng
Xiao-Fan Wang
Xiang Wang
Jing-Jing Li
Dong Xie
CHML promotes liver cancer metastasis by facilitating Rab14 recycle
description Metastasis-associated recurrence is a major cause of poor prognosis in hepatocellular carcinoma. Here, the authors show that expression of choroideremia-like (CHML) is elevated and associates with poor prognosis in hepatocellular carcinoma, and mechanistically CHML promotes metastasis in a Rab14-dependent manner.
format article
author Tian-Wei Chen
Fen-Fen Yin
Yan-Mei Yuan
Dong-Xian Guan
Erbin Zhang
Feng-Kun Zhang
Hao Jiang
Ning Ma
Jing-Jing Wang
Qian-Zhi Ni
Lin Qiu
Jing Feng
Xue-Li Zhang
Ying Bao
Kang Wang
Shu-Qun Cheng
Xiao-Fan Wang
Xiang Wang
Jing-Jing Li
Dong Xie
author_facet Tian-Wei Chen
Fen-Fen Yin
Yan-Mei Yuan
Dong-Xian Guan
Erbin Zhang
Feng-Kun Zhang
Hao Jiang
Ning Ma
Jing-Jing Wang
Qian-Zhi Ni
Lin Qiu
Jing Feng
Xue-Li Zhang
Ying Bao
Kang Wang
Shu-Qun Cheng
Xiao-Fan Wang
Xiang Wang
Jing-Jing Li
Dong Xie
author_sort Tian-Wei Chen
title CHML promotes liver cancer metastasis by facilitating Rab14 recycle
title_short CHML promotes liver cancer metastasis by facilitating Rab14 recycle
title_full CHML promotes liver cancer metastasis by facilitating Rab14 recycle
title_fullStr CHML promotes liver cancer metastasis by facilitating Rab14 recycle
title_full_unstemmed CHML promotes liver cancer metastasis by facilitating Rab14 recycle
title_sort chml promotes liver cancer metastasis by facilitating rab14 recycle
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/dc0b4bcc791f411d85b4e5b46c2d6ddb
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