Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen <italic toggle="yes">Balamuthia mandrillaris</italic>

ABSTRACT Balamuthia mandrillaris is a pathogenic free-living amoeba that causes a rare but almost always fatal infection of the central nervous system called granulomatous amoebic encephalitis (GAE). Two distinct forms of B. mandrillaris—a proliferative trophozoite form and a nonproliferative cyst f...

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Autores principales: Matthew T. Laurie, Corin V. White, Hanna Retallack, Wesley Wu, Matthew S. Moser, Judy A. Sakanari, Kenny Ang, Christopher Wilson, Michelle R. Arkin, Joseph L. DeRisi
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://doaj.org/article/dc0b924a0e4e4116b009021d93f76abd
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