FICD activity and AMPylation remodelling modulate human neurogenesis

Protein AMPylation is a post-translational modification whose implications in cellular physiology are not fully understood. Here the authors develop a cell-permeable AMPylation probe and use it to identify new AMP modified proteins and investigate the role of FICD in neuronal differentiation using c...

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Auteurs principaux: Pavel Kielkowski, Isabel Y. Buchsbaum, Volker C. Kirsch, Nina C. Bach, Micha Drukker, Silvia Cappello, Stephan A. Sieber
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/dc0d7f0727124aa5ad2c40e99753071c
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