Molecular mechanism of thiazolidinedione-mediated inhibitory effects on osteoclastogenesis.

Thiazolidinediones are synthetic peroxisome proliferator-activated receptor γ agonists used to treat type 2 diabetes mellitus. Clinical evidence indicates that thiazolidinediones increase fracture risks in type 2 diabetes mellitus patients, but the mechanism by which thiazolidinediones augment fract...

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Autores principales: Dongfeng Zhao, Zhenqi Shi, Amy H Warriner, Ping Qiao, Huixian Hong, Yongjun Wang, Xu Feng
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/dc16db73d1cb4e6f8503783122d9df53
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