The binding of Borealin to microtubules underlies a tension independent kinetochore-microtubule error correction pathway
How the chromosome passenger complex (CPC) phosphorylates the kinetochores that can be a micron away to control mitotic events is unknown. Here the authors find that the CPC directly binds microtubules near inner centromeres, which controls its ability to phosphorylate kinetochores independently of...
Guardado en:
Autores principales: | Prasad Trivedi, Anatoly V. Zaytsev, Maxim Godzi, Fazly I. Ataullakhanov, Ekaterina L. Grishchuk, P. Todd Stukenberg |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/dc1b2464d5e3480a863990aff60e55d7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity
por: Manas Chakraborty, et al.
Publicado: (2019) -
Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments
por: Damian Dudka, et al.
Publicado: (2018) -
Are microtubules tension sensors?
por: Olivier Hamant, et al.
Publicado: (2019) -
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
por: Janko Kajtez, et al.
Publicado: (2016) -
Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
por: Roshan L. Shrestha, et al.
Publicado: (2017)