Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells

Correct spindle positioning is critical for cell division but the full set of proteins regulating this is unclear. Here, with a live imaging siRNA-based screen in human cells, the authors identify 16 candidates required for this process, 11 of which were previously unassociated with such a function,...

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Autores principales:	Benita Wolf, Coralie Busso, Pierre Gönczy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dc1c4c62f71940c7926647e7846ea1ab
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spelling	oai:doaj.org-article:dc1c4c62f71940c7926647e7846ea1ab2021-12-02T14:39:19ZLive imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells10.1038/s41467-019-10446-z2041-1723https://doaj.org/article/dc1c4c62f71940c7926647e7846ea1ab2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10446-zhttps://doaj.org/toc/2041-1723Correct spindle positioning is critical for cell division but the full set of proteins regulating this is unclear. Here, with a live imaging siRNA-based screen in human cells, the authors identify 16 candidates required for this process, 11 of which were previously unassociated with such a function, including TYRO3 and GAK.Benita WolfCoralie BussoPierre GönczyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benita Wolf Coralie Busso Pierre Gönczy Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells
description	Correct spindle positioning is critical for cell division but the full set of proteins regulating this is unclear. Here, with a live imaging siRNA-based screen in human cells, the authors identify 16 candidates required for this process, 11 of which were previously unassociated with such a function, including TYRO3 and GAK.
format	article
author	Benita Wolf Coralie Busso Pierre Gönczy
author_facet	Benita Wolf Coralie Busso Pierre Gönczy
author_sort	Benita Wolf
title	Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells
title_short	Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells
title_full	Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells
title_fullStr	Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells
title_full_unstemmed	Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells
title_sort	live imaging screen reveals that tyro3 and gak ensure accurate spindle positioning in human cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/dc1c4c62f71940c7926647e7846ea1ab
work_keys_str_mv	AT benitawolf liveimagingscreenrevealsthattyro3andgakensureaccuratespindlepositioninginhumancells AT coraliebusso liveimagingscreenrevealsthattyro3andgakensureaccuratespindlepositioninginhumancells AT pierregonczy liveimagingscreenrevealsthattyro3andgakensureaccuratespindlepositioninginhumancells
_version_	1718390684378988544

Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells

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