Nitric oxide as a source for bacterial triazole biosynthesis

How nature creates 1,2,3-triazole ring is a relevant question to N-N bond biosynthesis. Here, the authors report the biosynthetic route to the triazole-bearing antimetabolite 8-azaguanine and reveal that this can be assembled through an enzymatic and non-enzymatic cascade, in which nitric oxide is u...

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Auteurs principaux: Guiyun Zhao, Yuan-Yang Guo, Shunyu Yao, Xinjie Shi, Longxian Lv, Yi-Ling Du
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/dc2b67cb367840399d4e3e65ee938fac
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