Hypertension in Women: Should There be a Sex-specific Threshold?

Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger ri...

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Autores principales: Eva Gerdts, Giovanni de Simone
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Lenguaje:EN
Publicado: Radcliffe Medical Media 2021
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Acceso en línea:https://doaj.org/article/dc2edaa9f39c401c84c20ee1850b2068
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spelling oai:doaj.org-article:dc2edaa9f39c401c84c20ee1850b20682021-12-04T16:05:05ZHypertension in Women: Should There be a Sex-specific Threshold?10.15420/ecr.2021.171758-37641758-3756https://doaj.org/article/dc2edaa9f39c401c84c20ee1850b20682021-10-01T00:00:00Zhttps://www.ecrjournal.com/articleindex/ecr.2021.17https://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger risk factor for cardiovascular disease (CVD) in women than men. While healthy young women have lower BP than men, a steeper increase in BP is found in women from the third decade of life. Studies have documented that the BP-attributable risk for acute coronary syndromes (ACS), heart failure and AF increases at a lower level of BP in women than in men. Even high normal BP (130–139/80–89 mmHg) is associated with an up to twofold higher risk of ACS during midlife in women, but not in men. Whether sex-specific thresholds for definition of hypertension would improve CVD risk detection should be considered in future guidelines for hypertension management and CVD prevention.Eva GerdtsGiovanni de SimoneRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 16, Iss , Pp - (2021)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Eva Gerdts
Giovanni de Simone
Hypertension in Women: Should There be a Sex-specific Threshold?
description Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger risk factor for cardiovascular disease (CVD) in women than men. While healthy young women have lower BP than men, a steeper increase in BP is found in women from the third decade of life. Studies have documented that the BP-attributable risk for acute coronary syndromes (ACS), heart failure and AF increases at a lower level of BP in women than in men. Even high normal BP (130–139/80–89 mmHg) is associated with an up to twofold higher risk of ACS during midlife in women, but not in men. Whether sex-specific thresholds for definition of hypertension would improve CVD risk detection should be considered in future guidelines for hypertension management and CVD prevention.
format article
author Eva Gerdts
Giovanni de Simone
author_facet Eva Gerdts
Giovanni de Simone
author_sort Eva Gerdts
title Hypertension in Women: Should There be a Sex-specific Threshold?
title_short Hypertension in Women: Should There be a Sex-specific Threshold?
title_full Hypertension in Women: Should There be a Sex-specific Threshold?
title_fullStr Hypertension in Women: Should There be a Sex-specific Threshold?
title_full_unstemmed Hypertension in Women: Should There be a Sex-specific Threshold?
title_sort hypertension in women: should there be a sex-specific threshold?
publisher Radcliffe Medical Media
publishDate 2021
url https://doaj.org/article/dc2edaa9f39c401c84c20ee1850b2068
work_keys_str_mv AT evagerdts hypertensioninwomenshouldtherebeasexspecificthreshold
AT giovannidesimone hypertensioninwomenshouldtherebeasexspecificthreshold
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