Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population

Abstract This study aimed to compare the values of new corneal visualization Scheimpflug technology (Corvis ST) parameters in normal, subclinical keratoconus (SKC) and keratoconus (KC) eyes, and evaluate the diagnostic ability to distinguish SKC and KC eyes from normal eyes. One-hundred normal, 100...

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Autores principales:	Shengwei Ren, Liyan Xu, Qi Fan, Yuwei Gu, Kaili Yang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/dc318d60561947af81534aec6541f513
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spelling	oai:doaj.org-article:dc318d60561947af81534aec6541f5132021-12-02T13:20:21ZAccuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population10.1038/s41598-021-84370-y2045-2322https://doaj.org/article/dc318d60561947af81534aec6541f5132021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84370-yhttps://doaj.org/toc/2045-2322Abstract This study aimed to compare the values of new corneal visualization Scheimpflug technology (Corvis ST) parameters in normal, subclinical keratoconus (SKC) and keratoconus (KC) eyes, and evaluate the diagnostic ability to distinguish SKC and KC eyes from normal eyes. One-hundred normal, 100 SKC and 100 KC eyes were included in the study. Corvis ST parameters containing dynamic corneal response parameters were measured by one ophthalmologist. The receiver operating characteristic curve was used to evaluate the diagnostic ability of new Corvis ST parameters. The new Corvis ST parameters in KC eyes were different from those in the control and SKC eyes after adjusting for IOP and CCT, and stiffness parameter at the first applanation (SP-A1) and Corvis biomechanical index (CBI) were significantly different between the control and SKC eyes (all P < 0.05). The parameter with the highest diagnostic efficiency was SP-A1 (Youden index = 0.40, AUC = 0.753), followed by CBI (Youden index = 0.38, AUC = 0.703), and Integrated Radius (Youden index = 0.33, AUC = 0.668) in diagnosing SKC from control eyes. New Corvis ST parameters in SKC eyes were significantly different from normal control and KC eyes, and could be considered to distinguish SKC and KC eyes from normal eyes.Shengwei RenLiyan XuQi FanYuwei GuKaili YangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Shengwei Ren Liyan Xu Qi Fan Yuwei Gu Kaili Yang Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population
description	Abstract This study aimed to compare the values of new corneal visualization Scheimpflug technology (Corvis ST) parameters in normal, subclinical keratoconus (SKC) and keratoconus (KC) eyes, and evaluate the diagnostic ability to distinguish SKC and KC eyes from normal eyes. One-hundred normal, 100 SKC and 100 KC eyes were included in the study. Corvis ST parameters containing dynamic corneal response parameters were measured by one ophthalmologist. The receiver operating characteristic curve was used to evaluate the diagnostic ability of new Corvis ST parameters. The new Corvis ST parameters in KC eyes were different from those in the control and SKC eyes after adjusting for IOP and CCT, and stiffness parameter at the first applanation (SP-A1) and Corvis biomechanical index (CBI) were significantly different between the control and SKC eyes (all P < 0.05). The parameter with the highest diagnostic efficiency was SP-A1 (Youden index = 0.40, AUC = 0.753), followed by CBI (Youden index = 0.38, AUC = 0.703), and Integrated Radius (Youden index = 0.33, AUC = 0.668) in diagnosing SKC from control eyes. New Corvis ST parameters in SKC eyes were significantly different from normal control and KC eyes, and could be considered to distinguish SKC and KC eyes from normal eyes.
format	article
author	Shengwei Ren Liyan Xu Qi Fan Yuwei Gu Kaili Yang
author_facet	Shengwei Ren Liyan Xu Qi Fan Yuwei Gu Kaili Yang
author_sort	Shengwei Ren
title	Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population
title_short	Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population
title_full	Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population
title_fullStr	Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population
title_full_unstemmed	Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population
title_sort	accuracy of new corvis st parameters for detecting subclinical and clinical keratoconus eyes in a chinese population
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/dc318d60561947af81534aec6541f513
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Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population

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