Overexpression of the transcribed ultraconserved region Uc.138 accelerates colon cancer progression

Abstract Ultraconserved regions (UCRs) are 481 genomic sequences with 100% identity across humans, rats, and mice. Increasing evidence suggests that non-coding RNAs transcribed from UCRs are involved in various diseases, especially cancers. The human transformer 2β gene (TRA2B) encodes a UCR (uc.138...

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Autores principales: Yuki Kuwano, Kensei Nishida, Kazuhito Rokutan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/dc353caf2da04beabca761a3929fbb4b
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