Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020

The 10th and largest Ebola virus disease epidemic in the Democratic Republic of the Congo (DRC) was declared in North Kivu Province in August 2018 and ended in June 2020. We describe and evaluate an Early Warning, Alert and Response System (EWARS) implemented in the Beni health zone of DRC during A...

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Autores principales: Mory Keita, Héloïse Lucaccioni, Michel Kalongo Ilumbulumbu, Jonathan Polonsky, Justus Nsio-Mbeta, Gaston Tshapenda Panda, Pierre Celeste Adikey, John Kombe Ngwama, Michel Kasereka Tosalisana, Boubacar Diallo, Lorenzo Subissi, Adama Dakissaga, Iris Finci, Maria Moitinho de Almeida, Debarati Guha-Sapir, Ambrose Talisuna, Alexandre Delamou, Stephanie Dagron, Olivia Keiser, Steve Ahuka-Mundeke
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Publicado: Centers for Disease Control and Prevention 2021
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Acceso en línea:https://doaj.org/article/dc356b324da0400e9b6e21c805d697a2
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spelling oai:doaj.org-article:dc356b324da0400e9b6e21c805d697a22021-11-22T12:56:19ZEvaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–202010.3201/eid2712.2102901080-60401080-6059https://doaj.org/article/dc356b324da0400e9b6e21c805d697a22021-12-01T00:00:00Zhttps://wwwnc.cdc.gov/eid/article/27/12/21-0290_articlehttps://doaj.org/toc/1080-6040https://doaj.org/toc/1080-6059 The 10th and largest Ebola virus disease epidemic in the Democratic Republic of the Congo (DRC) was declared in North Kivu Province in August 2018 and ended in June 2020. We describe and evaluate an Early Warning, Alert and Response System (EWARS) implemented in the Beni health zone of DRC during August 5, 2018–June 30, 2020. During this period, 194,768 alerts were received, of which 30,728 (15.8%) were validated as suspected cases. From these, 801 confirmed and 3 probable cases were detected. EWARS showed an overall good performance: sensitivity and specificity >80%, nearly all (97%) of alerts investigated within 2 hours of notification, and good demographic representativeness. The average cost of the system was US $438/case detected and US $1.8/alert received. The system was stable, despite occasional disruptions caused by political insecurity. Our results demonstrate that EWARS was a cost-effective component of the Ebola surveillance strategy in this setting. Mory KeitaHéloïse LucaccioniMichel Kalongo IlumbulumbuJonathan PolonskyJustus Nsio-MbetaGaston Tshapenda PandaPierre Celeste AdikeyJohn Kombe NgwamaMichel Kasereka TosalisanaBoubacar DialloLorenzo SubissiAdama DakissagaIris FinciMaria Moitinho de AlmeidaDebarati Guha-SapirAmbrose TalisunaAlexandre DelamouStephanie DagronOlivia KeiserSteve Ahuka-MundekeCenters for Disease Control and PreventionarticleEbolaEbola virus infectionvirusesEarly Warning Alert and Response SystemEWARSsurveillanceMedicineRInfectious and parasitic diseasesRC109-216ENEmerging Infectious Diseases, Vol 27, Iss 12, Pp 2988-2998 (2021)
institution DOAJ
collection DOAJ
language EN
topic Ebola
Ebola virus infection
viruses
Early Warning Alert and Response System
EWARS
surveillance
Medicine
R
Infectious and parasitic diseases
RC109-216
spellingShingle Ebola
Ebola virus infection
viruses
Early Warning Alert and Response System
EWARS
surveillance
Medicine
R
Infectious and parasitic diseases
RC109-216
Mory Keita
Héloïse Lucaccioni
Michel Kalongo Ilumbulumbu
Jonathan Polonsky
Justus Nsio-Mbeta
Gaston Tshapenda Panda
Pierre Celeste Adikey
John Kombe Ngwama
Michel Kasereka Tosalisana
Boubacar Diallo
Lorenzo Subissi
Adama Dakissaga
Iris Finci
Maria Moitinho de Almeida
Debarati Guha-Sapir
Ambrose Talisuna
Alexandre Delamou
Stephanie Dagron
Olivia Keiser
Steve Ahuka-Mundeke
Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020
description The 10th and largest Ebola virus disease epidemic in the Democratic Republic of the Congo (DRC) was declared in North Kivu Province in August 2018 and ended in June 2020. We describe and evaluate an Early Warning, Alert and Response System (EWARS) implemented in the Beni health zone of DRC during August 5, 2018–June 30, 2020. During this period, 194,768 alerts were received, of which 30,728 (15.8%) were validated as suspected cases. From these, 801 confirmed and 3 probable cases were detected. EWARS showed an overall good performance: sensitivity and specificity >80%, nearly all (97%) of alerts investigated within 2 hours of notification, and good demographic representativeness. The average cost of the system was US $438/case detected and US $1.8/alert received. The system was stable, despite occasional disruptions caused by political insecurity. Our results demonstrate that EWARS was a cost-effective component of the Ebola surveillance strategy in this setting.
format article
author Mory Keita
Héloïse Lucaccioni
Michel Kalongo Ilumbulumbu
Jonathan Polonsky
Justus Nsio-Mbeta
Gaston Tshapenda Panda
Pierre Celeste Adikey
John Kombe Ngwama
Michel Kasereka Tosalisana
Boubacar Diallo
Lorenzo Subissi
Adama Dakissaga
Iris Finci
Maria Moitinho de Almeida
Debarati Guha-Sapir
Ambrose Talisuna
Alexandre Delamou
Stephanie Dagron
Olivia Keiser
Steve Ahuka-Mundeke
author_facet Mory Keita
Héloïse Lucaccioni
Michel Kalongo Ilumbulumbu
Jonathan Polonsky
Justus Nsio-Mbeta
Gaston Tshapenda Panda
Pierre Celeste Adikey
John Kombe Ngwama
Michel Kasereka Tosalisana
Boubacar Diallo
Lorenzo Subissi
Adama Dakissaga
Iris Finci
Maria Moitinho de Almeida
Debarati Guha-Sapir
Ambrose Talisuna
Alexandre Delamou
Stephanie Dagron
Olivia Keiser
Steve Ahuka-Mundeke
author_sort Mory Keita
title Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020
title_short Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020
title_full Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020
title_fullStr Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020
title_full_unstemmed Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020
title_sort evaluation of early warning, alert and response system for ebola virus disease, democratic republic of the congo, 2018–2020
publisher Centers for Disease Control and Prevention
publishDate 2021
url https://doaj.org/article/dc356b324da0400e9b6e21c805d697a2
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