CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

The co-transcriptional capping of transcripts synthesized by RNA Pol II is substantially more efficient than capping of free RNA, a process that has been shown to depend on CTD phosphorylation. Here the authors demonstrate that a CTD-independent mechanism functions in parallel with CTD-dependent pro...

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Autores principales:	Melvin Noe Gonzalez, Shigeo Sato, Chieri Tomomori-Sato, Joan W. Conaway, Ronald C. Conaway
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dc395454338c4cf1a9d7e246fb496ca9
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spelling	oai:doaj.org-article:dc395454338c4cf1a9d7e246fb496ca92021-12-02T17:31:13ZCTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts10.1038/s41467-018-05923-w2041-1723https://doaj.org/article/dc395454338c4cf1a9d7e246fb496ca92018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05923-whttps://doaj.org/toc/2041-1723The co-transcriptional capping of transcripts synthesized by RNA Pol II is substantially more efficient than capping of free RNA, a process that has been shown to depend on CTD phosphorylation. Here the authors demonstrate that a CTD-independent mechanism functions in parallel with CTD-dependent processes to ensure efficient capping.Melvin Noe GonzalezShigeo SatoChieri Tomomori-SatoJoan W. ConawayRonald C. ConawayNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Melvin Noe Gonzalez Shigeo Sato Chieri Tomomori-Sato Joan W. Conaway Ronald C. Conaway CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts
description	The co-transcriptional capping of transcripts synthesized by RNA Pol II is substantially more efficient than capping of free RNA, a process that has been shown to depend on CTD phosphorylation. Here the authors demonstrate that a CTD-independent mechanism functions in parallel with CTD-dependent processes to ensure efficient capping.
format	article
author	Melvin Noe Gonzalez Shigeo Sato Chieri Tomomori-Sato Joan W. Conaway Ronald C. Conaway
author_facet	Melvin Noe Gonzalez Shigeo Sato Chieri Tomomori-Sato Joan W. Conaway Ronald C. Conaway
author_sort	Melvin Noe Gonzalez
title	CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts
title_short	CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts
title_full	CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts
title_fullStr	CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts
title_full_unstemmed	CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts
title_sort	ctd-dependent and -independent mechanisms govern co-transcriptional capping of pol ii transcripts
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/dc395454338c4cf1a9d7e246fb496ca9
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CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

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