Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy
Study of human heart failure is limited by access to human tissue. Here, the authors apply multi-omic screening in human ischaemic and dilated myocardial tissue and matched controls to determine molecular changes common and unique to each aetiology and to reveal differences between male and female h...
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Nature Portfolio
2020
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oai:doaj.org-article:dc50dd89da9c42378ed20e5b3c379c662021-12-02T17:51:11ZCore functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy10.1038/s41467-020-16584-z2041-1723https://doaj.org/article/dc50dd89da9c42378ed20e5b3c379c662020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16584-zhttps://doaj.org/toc/2041-1723Study of human heart failure is limited by access to human tissue. Here, the authors apply multi-omic screening in human ischaemic and dilated myocardial tissue and matched controls to determine molecular changes common and unique to each aetiology and to reveal differences between male and female hearts.Mengbo LiBenjamin L. ParkerEvangeline PearsonBenjamin HunterJacob CaoYen Chin KoayOneka GuneratneDavid E. JamesJean YangSean LalJohn F. O’SullivanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020) |
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DOAJ |
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Science Q |
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Science Q Mengbo Li Benjamin L. Parker Evangeline Pearson Benjamin Hunter Jacob Cao Yen Chin Koay Oneka Guneratne David E. James Jean Yang Sean Lal John F. O’Sullivan Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy |
description |
Study of human heart failure is limited by access to human tissue. Here, the authors apply multi-omic screening in human ischaemic and dilated myocardial tissue and matched controls to determine molecular changes common and unique to each aetiology and to reveal differences between male and female hearts. |
format |
article |
author |
Mengbo Li Benjamin L. Parker Evangeline Pearson Benjamin Hunter Jacob Cao Yen Chin Koay Oneka Guneratne David E. James Jean Yang Sean Lal John F. O’Sullivan |
author_facet |
Mengbo Li Benjamin L. Parker Evangeline Pearson Benjamin Hunter Jacob Cao Yen Chin Koay Oneka Guneratne David E. James Jean Yang Sean Lal John F. O’Sullivan |
author_sort |
Mengbo Li |
title |
Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy |
title_short |
Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy |
title_full |
Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy |
title_fullStr |
Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy |
title_full_unstemmed |
Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy |
title_sort |
core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/dc50dd89da9c42378ed20e5b3c379c66 |
work_keys_str_mv |
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1718379318420176896 |