Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy

Study of human heart failure is limited by access to human tissue. Here, the authors apply multi-omic screening in human ischaemic and dilated myocardial tissue and matched controls to determine molecular changes common and unique to each aetiology and to reveal differences between male and female h...

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Autores principales: Mengbo Li, Benjamin L. Parker, Evangeline Pearson, Benjamin Hunter, Jacob Cao, Yen Chin Koay, Oneka Guneratne, David E. James, Jean Yang, Sean Lal, John F. O’Sullivan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/dc50dd89da9c42378ed20e5b3c379c66
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spelling oai:doaj.org-article:dc50dd89da9c42378ed20e5b3c379c662021-12-02T17:51:11ZCore functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy10.1038/s41467-020-16584-z2041-1723https://doaj.org/article/dc50dd89da9c42378ed20e5b3c379c662020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16584-zhttps://doaj.org/toc/2041-1723Study of human heart failure is limited by access to human tissue. Here, the authors apply multi-omic screening in human ischaemic and dilated myocardial tissue and matched controls to determine molecular changes common and unique to each aetiology and to reveal differences between male and female hearts.Mengbo LiBenjamin L. ParkerEvangeline PearsonBenjamin HunterJacob CaoYen Chin KoayOneka GuneratneDavid E. JamesJean YangSean LalJohn F. O’SullivanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mengbo Li
Benjamin L. Parker
Evangeline Pearson
Benjamin Hunter
Jacob Cao
Yen Chin Koay
Oneka Guneratne
David E. James
Jean Yang
Sean Lal
John F. O’Sullivan
Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy
description Study of human heart failure is limited by access to human tissue. Here, the authors apply multi-omic screening in human ischaemic and dilated myocardial tissue and matched controls to determine molecular changes common and unique to each aetiology and to reveal differences between male and female hearts.
format article
author Mengbo Li
Benjamin L. Parker
Evangeline Pearson
Benjamin Hunter
Jacob Cao
Yen Chin Koay
Oneka Guneratne
David E. James
Jean Yang
Sean Lal
John F. O’Sullivan
author_facet Mengbo Li
Benjamin L. Parker
Evangeline Pearson
Benjamin Hunter
Jacob Cao
Yen Chin Koay
Oneka Guneratne
David E. James
Jean Yang
Sean Lal
John F. O’Sullivan
author_sort Mengbo Li
title Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy
title_short Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy
title_full Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy
title_fullStr Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy
title_full_unstemmed Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy
title_sort core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/dc50dd89da9c42378ed20e5b3c379c66
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