Fluconazole-Induced Ploidy Change in <named-content content-type="genus-species">Cryptococcus neoformans</named-content> Results from the Uncoupling of Cell Growth and Nuclear Division

Fluconazole-Induced Ploidy Change in <named-content content-type="genus-species">Cryptococcus neoformans</named-content> Results from the Uncoupling of Cell Growth and Nuclear Division

ABSTRACT Cryptococcus neoformans is a pathogenic yeast that causes lethal cryptococcal meningitis in immunocompromised patients. One of the challenges in treating cryptococcosis is the development of resistance to azole antifungals. Previous studies linked azole resistance to elevated numbers of cop...

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Autores principales: Sophie Altamirano, Diana Fang, Charles Simmons, Shreyas Sridhar, Peipei Wu, Kaustuv Sanyal, Lukasz Kozubowski
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
antifungal resistance
cytokinesis
heteroresistance
ploidy
yeasts
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/dc667f1f4bd3429fa3da9ec4cb974f89
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