Evolutionary Landscape of the <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Complex from the Viewpoint of PhoPR: Implications for Virulence Regulation and Application to Vaccine Development

ABSTRACT Different members of the Mycobacterium genus have evolved to cause tuberculosis in diverse human populations and in a variety of animal species. Our cumulative knowledge of mycobacterial genomes indicates that mutations in the PhoPR two-component virulence system were acquired not only duri...

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Autores principales: Esther Broset, Carlos Martín, Jesús Gonzalo-Asensio
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/dc68ad2f42ef426fa0c0e7ef283f2033
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