Constitutive β-catenin signaling by the viral chemokine receptor US28.

Constitutive β-catenin signaling by the viral chemokine receptor US28.

Chronic activation of Wnt/β-catenin signaling is found in a variety of human malignancies including melanoma, colorectal and hepatocellular carcinomas. Interestingly, expression of the HCMV-encoded chemokine receptor US28 in intestinal epithelial cells promotes intestinal neoplasia in transgenic mic...

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Bibliographic Details
Main Authors: Ellen V Langemeijer, Erik Slinger, Sabrina de Munnik, Andreas Schreiber, David Maussang, Henry Vischer, Folkert Verkaar, Rob Leurs, Marco Siderius, Martine J Smit
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/dc6c07a9a5084249b47881e5dc3e6aaf
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