Transcriptomic and Single-Cell Analysis Reveals Regulatory Networks and Cellular Heterogeneity in Mouse Primary Sjögren’s Syndrome Salivary Glands

Transcriptomic and Single-Cell Analysis Reveals Regulatory Networks and Cellular Heterogeneity in Mouse Primary Sjögren’s Syndrome Salivary Glands

Sjögren’s Syndrome (SS) is a chronic autoimmune disease of unknown etiology which primarily affects the salivary and lacrimal glands resulting in the loss of secretory function. Treatment options for SS have been hampered due to the lack of a better understanding of the underlying gene regulatory ci...

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Detalles Bibliográficos
Autores principales: Erich Horeth, Akinsola Oyelakin, Eun-Ah Christine Song, Monika Che, Jonathan Bard, Sangwon Min, Jeremy Kiripolsky, Jill M. Kramer, Satrajit Sinha, Rose-Anne Romano
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
primary Sjögren’s syndrome
salivary glands
RNA-sequencing
single cell RNA-sequencing
gene expression
genomics
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/dc6e5442713e441cae4198893ed50266
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