Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor.
Imaging techniques based on fluorescence and bioluminescence have been important tools in visualizing tumor progression and studying the effect of drugs and immunotherapies on tumor immune microenvironment in animal models of cancer. However, transgenic expression of foreign proteins may induce immu...
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Auteurs principaux: | Lei Huang, Ramireddy Bommireddy, Luis E Munoz, Rohini N Guin, Changyong Wei, Amanda Ruggieri, Ashwathi P Menon, Xiaoxian Li, Mala Shanmugam, Taofeek K Owonikoko, Suresh S Ramalingam, Periasamy Selvaraj |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2021
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Accès en ligne: | https://doaj.org/article/dc6e930ff2a44d15a2ac8e0dd7a119d8 |
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