Inhibition of CMP-sialic acid transport by endogenous 5-methyl CMP.
Nucleotide-sugar transporters (NSTs) transport nucleotide-sugar conjugates into the Golgi lumen where they are then used in the synthesis of glycans. We previously reported crystal structures of a mammalian NST, the CMP-sialic acid transporter (CST) (Ahuja and Whorton 2019). These structures elucida...
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Autores principales: | Shivani Ahuja, James Cahill, Kimberly Hartfield, Matthew R Whorton |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/dc80040564154a17b895075e23eeecd9 |
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