Selection of potent non-toxic inhibitory sequences from a randomized HIV-1 specific lentiviral short hairpin RNA library.

RNA interference (RNAi) has been considered as an efficient therapeutic approach against the human immunodeficiency virus type 1 (HIV-1). However, to establish a durable inhibition of HIV-1, multiple effective short hairpin RNAs (shRNAs) need to be stably expressed to prevent the emergence of viral...

Full description

Saved in:
Bibliographic Details
Main Authors: Carola Pongratz, Benjamin Yazdanpanah, Hamid Kashkar, Maik J Lehmann, Hans-Georg Kräusslich, Martin Krönke
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
R
Q
Online Access:https://doaj.org/article/dc8f010013af4309bf754b005fde4b6f
Tags: Add Tag
No Tags, Be the first to tag this record!