Dural Follicular Lymphoma: Case Report and Literature Review

Follicular lymphoma (FL) usually has an indolent course and presents with painless, waxing and waning lymphadenopathy in the absence of systemic symptoms. It is uncommon for FL to present outside of lymph nodes, although it can develop in the gastrointestinal tract, skin, thyroid, and testes. Centra...

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Autores principales:	Ellery Altshuler MD, Raymond Richhart MD, Umar Iqbal MD, Joanna Chaffin MD
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Medicine (General) R5-920 Pathology RB1-214
Acceso en línea:	https://doaj.org/article/dcb601900b6247fcaa67d79377d5277d
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spelling	oai:doaj.org-article:dcb601900b6247fcaa67d79377d5277d2021-12-01T02:02:42ZDural Follicular Lymphoma: Case Report and Literature Review2324-709610.1177/23247096211056768https://doaj.org/article/dcb601900b6247fcaa67d79377d5277d2021-11-01T00:00:00Zhttps://doi.org/10.1177/23247096211056768https://doaj.org/toc/2324-7096Follicular lymphoma (FL) usually has an indolent course and presents with painless, waxing and waning lymphadenopathy in the absence of systemic symptoms. It is uncommon for FL to present outside of lymph nodes, although it can develop in the gastrointestinal tract, skin, thyroid, and testes. Central nervous system (CNS) involvement in FL is rare. Most CNS lymphomas are diffuse large B-cell lymphoma, although Burkitt lymphoma, lymphoblastic lymphoma, and peripheral T-cell lymphoma are also observed. These tumors usually involve white matter but may also involve gray matter. Lymphomas of the dura are very uncommon and are usually mucosa-associated lymphoid tissue lymphomas. Here, we present a case of FL of the dura arising in a 62-year-old woman that was responsive to chemotherapy. According to a literature review, there have been 15 previously reported cases of FL of the dura. Dural FL has been most frequently treated with radiation and chemotherapy. Patients were still alive in all cases in which follow-up was reported. Although the sample size is small, these data suggest that dural FL, like other forms of FL, is an indolent disease that is associated with prolonged survival despite usually being incurable.Ellery Altshuler MDRaymond Richhart MDUmar Iqbal MDJoanna Chaffin MDSAGE PublishingarticleMedicine (General)R5-920PathologyRB1-214ENJournal of Investigative Medicine High Impact Case Reports, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920 Pathology RB1-214
spellingShingle	Medicine (General) R5-920 Pathology RB1-214 Ellery Altshuler MD Raymond Richhart MD Umar Iqbal MD Joanna Chaffin MD Dural Follicular Lymphoma: Case Report and Literature Review
description	Follicular lymphoma (FL) usually has an indolent course and presents with painless, waxing and waning lymphadenopathy in the absence of systemic symptoms. It is uncommon for FL to present outside of lymph nodes, although it can develop in the gastrointestinal tract, skin, thyroid, and testes. Central nervous system (CNS) involvement in FL is rare. Most CNS lymphomas are diffuse large B-cell lymphoma, although Burkitt lymphoma, lymphoblastic lymphoma, and peripheral T-cell lymphoma are also observed. These tumors usually involve white matter but may also involve gray matter. Lymphomas of the dura are very uncommon and are usually mucosa-associated lymphoid tissue lymphomas. Here, we present a case of FL of the dura arising in a 62-year-old woman that was responsive to chemotherapy. According to a literature review, there have been 15 previously reported cases of FL of the dura. Dural FL has been most frequently treated with radiation and chemotherapy. Patients were still alive in all cases in which follow-up was reported. Although the sample size is small, these data suggest that dural FL, like other forms of FL, is an indolent disease that is associated with prolonged survival despite usually being incurable.
format	article
author	Ellery Altshuler MD Raymond Richhart MD Umar Iqbal MD Joanna Chaffin MD
author_facet	Ellery Altshuler MD Raymond Richhart MD Umar Iqbal MD Joanna Chaffin MD
author_sort	Ellery Altshuler MD
title	Dural Follicular Lymphoma: Case Report and Literature Review
title_short	Dural Follicular Lymphoma: Case Report and Literature Review
title_full	Dural Follicular Lymphoma: Case Report and Literature Review
title_fullStr	Dural Follicular Lymphoma: Case Report and Literature Review
title_full_unstemmed	Dural Follicular Lymphoma: Case Report and Literature Review
title_sort	dural follicular lymphoma: case report and literature review
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/dcb601900b6247fcaa67d79377d5277d
work_keys_str_mv	AT elleryaltshulermd duralfollicularlymphomacasereportandliteraturereview AT raymondrichhartmd duralfollicularlymphomacasereportandliteraturereview AT umariqbalmd duralfollicularlymphomacasereportandliteraturereview AT joannachaffinmd duralfollicularlymphomacasereportandliteraturereview
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Dural Follicular Lymphoma: Case Report and Literature Review

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