The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium

Mohamed A FakhryDepartment of Ophthalmology, Kasr El Aini Hospital, Cairo University, Cairo, EgyptPurpose: The purpose of this study is to evaluate and compare recurrence rates upon using mitomycin C (MMC) with limbal-conjunctival autograft for treating recurrent pterygia.Methodology: An interventio...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Mohamed A Fakhry
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/dcb8bd89b38e4cddb41ad4dbda37259a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:dcb8bd89b38e4cddb41ad4dbda37259a
record_format	dspace
spelling	oai:doaj.org-article:dcb8bd89b38e4cddb41ad4dbda37259a2021-12-02T02:32:36ZThe use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium1177-54671177-5483https://doaj.org/article/dcb8bd89b38e4cddb41ad4dbda37259a2011-01-01T00:00:00Zhttp://www.dovepress.com/the-use-of-mitomycin-c-with-autologous-limbal-conjunctival-autograft-t-a6150https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Mohamed A FakhryDepartment of Ophthalmology, Kasr El Aini Hospital, Cairo University, Cairo, EgyptPurpose: The purpose of this study is to evaluate and compare recurrence rates upon using mitomycin C (MMC) with limbal-conjunctival autograft for treating recurrent pterygia.Methodology: An interventional, prospective, comparative clinical study was performed in 30 eyes (26 patients) with recurrent pterygia, allocated into two groups: Group A (19 eyes) operated by pterygium excision and limbal-conjunctival autograft transplantation (L-CAT) without MMC and Group B (20 eyes) operated with injection of 0.1 mL of MMC 0.15 mg/mL 1 month before L-CAT surgery. Exclusion criteria included patients with symblepharon, cicatricial conjunctival diseases, limbal stem cell deficiency, and other intraocular diseases.Results: A total of four cases of recurrences for Group A (P = 0.012) and one case of recurrence for Group B (P &lt; 0.001) were recorded.Conclusions: Preoperative injection of MMC in low dose and concentration improves the results of L-CAT in recurrent pterygium.Keywords: recurrent pterygium, limbal autograft, conjunctival autograft, mitomycin C Mohamed A FakhryDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 123-127 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Mohamed A Fakhry The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium
description	Mohamed A FakhryDepartment of Ophthalmology, Kasr El Aini Hospital, Cairo University, Cairo, EgyptPurpose: The purpose of this study is to evaluate and compare recurrence rates upon using mitomycin C (MMC) with limbal-conjunctival autograft for treating recurrent pterygia.Methodology: An interventional, prospective, comparative clinical study was performed in 30 eyes (26 patients) with recurrent pterygia, allocated into two groups: Group A (19 eyes) operated by pterygium excision and limbal-conjunctival autograft transplantation (L-CAT) without MMC and Group B (20 eyes) operated with injection of 0.1 mL of MMC 0.15 mg/mL 1 month before L-CAT surgery. Exclusion criteria included patients with symblepharon, cicatricial conjunctival diseases, limbal stem cell deficiency, and other intraocular diseases.Results: A total of four cases of recurrences for Group A (P = 0.012) and one case of recurrence for Group B (P &lt; 0.001) were recorded.Conclusions: Preoperative injection of MMC in low dose and concentration improves the results of L-CAT in recurrent pterygium.Keywords: recurrent pterygium, limbal autograft, conjunctival autograft, mitomycin C
format	article
author	Mohamed A Fakhry
author_facet	Mohamed A Fakhry
author_sort	Mohamed A Fakhry
title	The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium
title_short	The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium
title_full	The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium
title_fullStr	The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium
title_full_unstemmed	The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium
title_sort	use of mitomycin c with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/dcb8bd89b38e4cddb41ad4dbda37259a
work_keys_str_mv	AT mohamedafakhry theuseofmitomycincwithautologouslimbalconjunctivalautografttransplantationformanagementofrecurrentpterygium AT mohamedafakhry useofmitomycincwithautologouslimbalconjunctivalautografttransplantationformanagementofrecurrentpterygium
_version_	1718402442342694912

The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium

Ejemplares similares