CRISPR/Cas9-mediated mutation of tyrosinase (Tyr) 3′ UTR induce graying in rabbit

CRISPR/Cas9-mediated mutation of tyrosinase (Tyr) 3′ UTR induce graying in rabbit

Abstract The 3′ untranslated regions (UTRs), located at the end of mRNA molecules, are believed to play a role in RNA replication and/or protein translation. Mutations in the tyrosinase (Tyr) gene are known to cause recessive albinism in humans and other species. In this study, to test whether the C...

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Autores principales: Yuning Song, Yuxin Xu, Jichao Deng, Mao Chen, Yi Lu, Yong Wang, Haobin Yao, Lina Zhou, Zhiquan Liu, Liangxue Lai, Zhanjun Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/dcbff7bfe93b414a844ee6c0defd2634
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