Neutrophil-derived reactive oxygen species promote tumor colonization

Zhong et al. investigate how mutations in the NOX2 subunit Ncf1 lead to reduced ROS formation and affect B16F10 lung metastasis. The study highlights neutrophils as key to detrimental ROS-formation and suggest the involvement of IL-1 beta and RAGE.

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Autores principales:	Jianghong Zhong, Qijing Li, Huqiao Luo, Rikard Holmdahl
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/dcc015fbb2bc41d0aa67b18ff8fcbeac
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spelling	oai:doaj.org-article:dcc015fbb2bc41d0aa67b18ff8fcbeac2021-12-02T18:30:44ZNeutrophil-derived reactive oxygen species promote tumor colonization10.1038/s42003-021-02376-82399-3642https://doaj.org/article/dcc015fbb2bc41d0aa67b18ff8fcbeac2021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02376-8https://doaj.org/toc/2399-3642Zhong et al. investigate how mutations in the NOX2 subunit Ncf1 lead to reduced ROS formation and affect B16F10 lung metastasis. The study highlights neutrophils as key to detrimental ROS-formation and suggest the involvement of IL-1 beta and RAGE.Jianghong ZhongQijing LiHuqiao LuoRikard HolmdahlNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Jianghong Zhong Qijing Li Huqiao Luo Rikard Holmdahl Neutrophil-derived reactive oxygen species promote tumor colonization
description	Zhong et al. investigate how mutations in the NOX2 subunit Ncf1 lead to reduced ROS formation and affect B16F10 lung metastasis. The study highlights neutrophils as key to detrimental ROS-formation and suggest the involvement of IL-1 beta and RAGE.
format	article
author	Jianghong Zhong Qijing Li Huqiao Luo Rikard Holmdahl
author_facet	Jianghong Zhong Qijing Li Huqiao Luo Rikard Holmdahl
author_sort	Jianghong Zhong
title	Neutrophil-derived reactive oxygen species promote tumor colonization
title_short	Neutrophil-derived reactive oxygen species promote tumor colonization
title_full	Neutrophil-derived reactive oxygen species promote tumor colonization
title_fullStr	Neutrophil-derived reactive oxygen species promote tumor colonization
title_full_unstemmed	Neutrophil-derived reactive oxygen species promote tumor colonization
title_sort	neutrophil-derived reactive oxygen species promote tumor colonization
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/dcc015fbb2bc41d0aa67b18ff8fcbeac
work_keys_str_mv	AT jianghongzhong neutrophilderivedreactiveoxygenspeciespromotetumorcolonization AT qijingli neutrophilderivedreactiveoxygenspeciespromotetumorcolonization AT huqiaoluo neutrophilderivedreactiveoxygenspeciespromotetumorcolonization AT rikardholmdahl neutrophilderivedreactiveoxygenspeciespromotetumorcolonization
_version_	1718378010030112768

Neutrophil-derived reactive oxygen species promote tumor colonization

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