Neutrophil-derived reactive oxygen species promote tumor colonization

Neutrophil-derived reactive oxygen species promote tumor colonization

Zhong et al. investigate how mutations in the NOX2 subunit Ncf1 lead to reduced ROS formation and affect B16F10 lung metastasis. The study highlights neutrophils as key to detrimental ROS-formation and suggest the involvement of IL-1 beta and RAGE.

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Auteurs principaux: Jianghong Zhong, Qijing Li, Huqiao Luo, Rikard Holmdahl
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/dcc015fbb2bc41d0aa67b18ff8fcbeac
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spelling oai:doaj.org-article:dcc015fbb2bc41d0aa67b18ff8fcbeac2021-12-02T18:30:44ZNeutrophil-derived reactive oxygen species promote tumor colonization10.1038/s42003-021-02376-82399-3642https://doaj.org/article/dcc015fbb2bc41d0aa67b18ff8fcbeac2021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02376-8https://doaj.org/toc/2399-3642Zhong et al. investigate how mutations in the NOX2 subunit Ncf1 lead to reduced ROS formation and affect B16F10 lung metastasis. The study highlights neutrophils as key to detrimental ROS-formation and suggest the involvement of IL-1 beta and RAGE.Jianghong ZhongQijing LiHuqiao LuoRikard HolmdahlNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Jianghong Zhong
Qijing Li
Huqiao Luo
Rikard Holmdahl
Neutrophil-derived reactive oxygen species promote tumor colonization
description Zhong et al. investigate how mutations in the NOX2 subunit Ncf1 lead to reduced ROS formation and affect B16F10 lung metastasis. The study highlights neutrophils as key to detrimental ROS-formation and suggest the involvement of IL-1 beta and RAGE.
format article
author Jianghong Zhong
Qijing Li
Huqiao Luo
Rikard Holmdahl
author_facet Jianghong Zhong
Qijing Li
Huqiao Luo
Rikard Holmdahl
author_sort Jianghong Zhong
title Neutrophil-derived reactive oxygen species promote tumor colonization
title_short Neutrophil-derived reactive oxygen species promote tumor colonization
title_full Neutrophil-derived reactive oxygen species promote tumor colonization
title_fullStr Neutrophil-derived reactive oxygen species promote tumor colonization
title_full_unstemmed Neutrophil-derived reactive oxygen species promote tumor colonization
title_sort neutrophil-derived reactive oxygen species promote tumor colonization
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/dcc015fbb2bc41d0aa67b18ff8fcbeac
work_keys_str_mv AT jianghongzhong neutrophilderivedreactiveoxygenspeciespromotetumorcolonization
AT qijingli neutrophilderivedreactiveoxygenspeciespromotetumorcolonization
AT huqiaoluo neutrophilderivedreactiveoxygenspeciespromotetumorcolonization
AT rikardholmdahl neutrophilderivedreactiveoxygenspeciespromotetumorcolonization
_version_ 1718378010030112768

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