Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions

In bacteria, the Rho protein dislodges elongation complexes to terminate transcription, and the Mfd protein removes RNA polymerases (RNAPs) stalled at DNA lesions. Here, Jain et al. show that Rho also dissociates stalled RNAPs at DNA lesions, which may facilitate DNA repair and other DNA-dependent p...

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Autores principales:	Sriyans Jain, Richa Gupta, Ranjan Sen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dcc95dec92b044f8abc9e1182dca2d13
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spelling	oai:doaj.org-article:dcc95dec92b044f8abc9e1182dca2d132021-12-02T14:40:18ZRho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions10.1038/s41467-019-09146-52041-1723https://doaj.org/article/dcc95dec92b044f8abc9e1182dca2d132019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09146-5https://doaj.org/toc/2041-1723In bacteria, the Rho protein dislodges elongation complexes to terminate transcription, and the Mfd protein removes RNA polymerases (RNAPs) stalled at DNA lesions. Here, Jain et al. show that Rho also dissociates stalled RNAPs at DNA lesions, which may facilitate DNA repair and other DNA-dependent processes.Sriyans JainRicha GuptaRanjan SenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sriyans Jain Richa Gupta Ranjan Sen Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
description	In bacteria, the Rho protein dislodges elongation complexes to terminate transcription, and the Mfd protein removes RNA polymerases (RNAPs) stalled at DNA lesions. Here, Jain et al. show that Rho also dissociates stalled RNAPs at DNA lesions, which may facilitate DNA repair and other DNA-dependent processes.
format	article
author	Sriyans Jain Richa Gupta Ranjan Sen
author_facet	Sriyans Jain Richa Gupta Ranjan Sen
author_sort	Sriyans Jain
title	Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
title_short	Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
title_full	Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
title_fullStr	Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
title_full_unstemmed	Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
title_sort	rho-dependent transcription termination in bacteria recycles rna polymerases stalled at dna lesions
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/dcc95dec92b044f8abc9e1182dca2d13
work_keys_str_mv	AT sriyansjain rhodependenttranscriptionterminationinbacteriarecyclesrnapolymerasesstalledatdnalesions AT richagupta rhodependenttranscriptionterminationinbacteriarecyclesrnapolymerasesstalledatdnalesions AT ranjansen rhodependenttranscriptionterminationinbacteriarecyclesrnapolymerasesstalledatdnalesions
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Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions

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