Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.

Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.

Restless legs syndrome (RLS) is a common neurologic disorder characterized by nightly dysesthesias affecting the legs primarily during periods of rest and relieved by movement. RLS is a complex genetic disease and susceptibility factors in six genomic regions have been identified by means of genome-...

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Autores principales: Eva C Schulte, Katharina Schramm, Claudia Schurmann, Peter Lichtner, Christian Herder, Michael Roden, Christian Gieger, Annette Peters, Claudia Trenkwalder, Birgit Högl, Birgit Frauscher, Klaus Berger, Ingo Fietze, Nadine Gross, Karin Stiasny-Kolster, Wolfgang Oertel, Cornelius G Bachmann, Walter Paulus, Alexander Zimprich, Henry Völzke, Ulf Schminke, Matthias Nauck, Thomas Illig, Thomas Meitinger, Bertram Müller-Myhsok, Holger Prokisch, Juliane Winkelmann
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/dcd845a0744e4f0b8a8dd1202187450a
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