Thioridazine induces major changes in global gene expression and cell wall composition in methicillin-resistant Staphylococcus aureus USA300.
Subinhibitory concentrations of the neuroleptic drug thioridazine (TDZ) are well-known to enhance the killing of methicillin-resistant Staphylococcus aureus (MRSA) by β-lactam antibiotics, however, the mechanism underlying the synergy between TDZ and β-lactams is not fully understood. In the present...
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Auteurs principaux: | Mette Thorsing, Janne K Klitgaard, Magda L Atilano, Marianne N Skov, Hans Jørn Kolmos, Sérgio R Filipe, Birgitte H Kallipolitis |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/dcde5f5da72f45c79b27564732f55c01 |
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