Insufficient antibody validation challenges oestrogen receptor beta research
A large body of work into the role of oestrogen receptor b (ERb) in breast cancer is contradictory, hindering future progress. Here the authors conduct extensive validation of anti-ERb antibodies , and show that normal and cancerous breast tissue do not express ERb, consistent with RNA-seq data.
Guardado en:
Autores principales: | Sandra Andersson, Mårten Sundberg, Nusa Pristovsek, Ahmed Ibrahim, Philip Jonsson, Borbala Katona, Carl-Magnus Clausson, Agata Zieba, Margareta Ramström, Ola Söderberg, Cecilia Williams, Anna Asplund |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/dcdf449150464c8b9fd9103cfd32d3ef |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Correction: Corrigendum: Insufficient antibody validation challenges oestrogen receptor beta research
por: Sandra Andersson, et al.
Publicado: (2017) -
Impact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation
por: Pascal Gellert, et al.
Publicado: (2016) -
Oestrogen Inhibits Arterial Calcification by Promoting Autophagy
por: Yi-Qun Peng, et al.
Publicado: (2017) -
Prediction of Insufficient Beta-Lactam Concentrations in Extracorporeal Membranous Oxygenation Patients
por: Amandine Polain, et al.
Publicado: (2021) -
Diabetic Retinopathy and Insulin Insufficiency: Beta Cell Replacement as a Strategy to Prevent Blindness
por: Eli Ipp
Publicado: (2021)