An Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans

The enteric parasite, <i>Cryptosporidium</i> is a major cause of diarrhoeal illness in humans and animals worldwide. No effective therapeutics or vaccines are available and therefore control is dependent on understanding transmission dynamics. The development of molecular detection and t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Una Ryan, Alireza Zahedi, Yaoyu Feng, Lihua Xiao
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Cryptosporidium</i> zoonotic transmission molecular tools Veterinary medicine SF600-1100 Zoology QL1-991
Acceso en línea:	https://doaj.org/article/dce1e0eea8cf41689ce2abf5eb6b895b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:dce1e0eea8cf41689ce2abf5eb6b895b
record_format	dspace
spelling	oai:doaj.org-article:dce1e0eea8cf41689ce2abf5eb6b895b2021-11-25T16:21:21ZAn Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans10.3390/ani111133072076-2615https://doaj.org/article/dce1e0eea8cf41689ce2abf5eb6b895b2021-11-01T00:00:00Zhttps://www.mdpi.com/2076-2615/11/11/3307https://doaj.org/toc/2076-2615The enteric parasite, <i>Cryptosporidium</i> is a major cause of diarrhoeal illness in humans and animals worldwide. No effective therapeutics or vaccines are available and therefore control is dependent on understanding transmission dynamics. The development of molecular detection and typing tools has resulted in the identification of a large number of cryptic species and genotypes and facilitated our understanding of their potential for zoonotic transmission. Of the 44 recognised <i>Cryptosporidium</i> species and >120 genotypes, 19 species, and four genotypes have been reported in humans with <i>C. hominis, C. parvum, C. meleagridis, C. canis</i> and <i>C. felis</i> being the most prevalent. The development of typing tools that are still lacking some zoonotic species and genotypes and more extensive molecular epidemiological studies in countries where the potential for transmission is highest are required to further our understanding of this important zoonotic pathogen. Similarly, whole-genome sequencing (WGS) and amplicon next-generation sequencing (NGS) are important for more accurately tracking transmission and understanding the mechanisms behind host specificity.Una RyanAlireza ZahediYaoyu FengLihua XiaoMDPI AGarticle<i>Cryptosporidium</i>zoonotictransmissionmolecular toolsVeterinary medicineSF600-1100ZoologyQL1-991ENAnimals, Vol 11, Iss 3307, p 3307 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Cryptosporidium</i> zoonotic transmission molecular tools Veterinary medicine SF600-1100 Zoology QL1-991
spellingShingle	<i>Cryptosporidium</i> zoonotic transmission molecular tools Veterinary medicine SF600-1100 Zoology QL1-991 Una Ryan Alireza Zahedi Yaoyu Feng Lihua Xiao An Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans
description	The enteric parasite, <i>Cryptosporidium</i> is a major cause of diarrhoeal illness in humans and animals worldwide. No effective therapeutics or vaccines are available and therefore control is dependent on understanding transmission dynamics. The development of molecular detection and typing tools has resulted in the identification of a large number of cryptic species and genotypes and facilitated our understanding of their potential for zoonotic transmission. Of the 44 recognised <i>Cryptosporidium</i> species and >120 genotypes, 19 species, and four genotypes have been reported in humans with <i>C. hominis, C. parvum, C. meleagridis, C. canis</i> and <i>C. felis</i> being the most prevalent. The development of typing tools that are still lacking some zoonotic species and genotypes and more extensive molecular epidemiological studies in countries where the potential for transmission is highest are required to further our understanding of this important zoonotic pathogen. Similarly, whole-genome sequencing (WGS) and amplicon next-generation sequencing (NGS) are important for more accurately tracking transmission and understanding the mechanisms behind host specificity.
format	article
author	Una Ryan Alireza Zahedi Yaoyu Feng Lihua Xiao
author_facet	Una Ryan Alireza Zahedi Yaoyu Feng Lihua Xiao
author_sort	Una Ryan
title	An Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans
title_short	An Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans
title_full	An Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans
title_fullStr	An Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans
title_full_unstemmed	An Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans
title_sort	update on zoonotic <i>cryptosporidium</i> species and genotypes in humans
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/dce1e0eea8cf41689ce2abf5eb6b895b
work_keys_str_mv	AT unaryan anupdateonzoonoticicryptosporidiumispeciesandgenotypesinhumans AT alirezazahedi anupdateonzoonoticicryptosporidiumispeciesandgenotypesinhumans AT yaoyufeng anupdateonzoonoticicryptosporidiumispeciesandgenotypesinhumans AT lihuaxiao anupdateonzoonoticicryptosporidiumispeciesandgenotypesinhumans AT unaryan updateonzoonoticicryptosporidiumispeciesandgenotypesinhumans AT alirezazahedi updateonzoonoticicryptosporidiumispeciesandgenotypesinhumans AT yaoyufeng updateonzoonoticicryptosporidiumispeciesandgenotypesinhumans AT lihuaxiao updateonzoonoticicryptosporidiumispeciesandgenotypesinhumans
_version_	1718413231343534080

An Update on Zoonotic <i>Cryptosporidium</i> Species and Genotypes in Humans

Ejemplares similares