Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement

Herein, we propose an impedance spectroscopy method using a mode-switching nonsinusoidal oscillator and apply this method for measuring the impedance of biological tissues and continuous impedance measurement. To obtain impedance spectra over a wide frequency range, we fabricated a novel nonsinusoid...

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Autores principales:	Tomiharu Yamaguchi, Emiyu Ogawa, Akinori Ueno
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	capacitive coupling impedance spectroscopy nonsinusoidal oscillator DFT frequency switching biological application Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/dce32157d747439a8e195c48adcd00fb
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spelling	oai:doaj.org-article:dce32157d747439a8e195c48adcd00fb2021-11-11T18:59:53ZShort-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement10.3390/s212169511424-8220https://doaj.org/article/dce32157d747439a8e195c48adcd00fb2021-10-01T00:00:00Zhttps://www.mdpi.com/1424-8220/21/21/6951https://doaj.org/toc/1424-8220Herein, we propose an impedance spectroscopy method using a mode-switching nonsinusoidal oscillator and apply this method for measuring the impedance of biological tissues and continuous impedance measurement. To obtain impedance spectra over a wide frequency range, we fabricated a novel nonsinusoidal oscillator incorporating binary counters and analog switches. This oscillator could periodically switch oscillation frequency through the mode switching of the feedback resistor. From the oscillation waveform at each oscillation frequency of this circuit (oscillator), we determined the impedance spectrum of a measured object using the discrete-time Fourier transform. Subsequently, we obtained the broad impedance spectrum of the measured object by merging odd-order harmonic spectral components up to the 19th order for each oscillation frequency. From the measured spectrum, the resistive and capacitive components of the circuit simulating bioimpedance were estimated with high accuracy. Moreover, the proposed method was used to measure the impedance of porcine myocardium; changes in the impedance spectrum of the myocardial tissue due to coagulation could be measured. Furthermore, rapid variations in the resistance value of a CdS photocell could be continuously measured using the proposed method.Tomiharu YamaguchiEmiyu OgawaAkinori UenoMDPI AGarticlecapacitive couplingimpedance spectroscopynonsinusoidal oscillatorDFTfrequency switchingbiological applicationChemical technologyTP1-1185ENSensors, Vol 21, Iss 6951, p 6951 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	capacitive coupling impedance spectroscopy nonsinusoidal oscillator DFT frequency switching biological application Chemical technology TP1-1185
spellingShingle	capacitive coupling impedance spectroscopy nonsinusoidal oscillator DFT frequency switching biological application Chemical technology TP1-1185 Tomiharu Yamaguchi Emiyu Ogawa Akinori Ueno Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement
description	Herein, we propose an impedance spectroscopy method using a mode-switching nonsinusoidal oscillator and apply this method for measuring the impedance of biological tissues and continuous impedance measurement. To obtain impedance spectra over a wide frequency range, we fabricated a novel nonsinusoidal oscillator incorporating binary counters and analog switches. This oscillator could periodically switch oscillation frequency through the mode switching of the feedback resistor. From the oscillation waveform at each oscillation frequency of this circuit (oscillator), we determined the impedance spectrum of a measured object using the discrete-time Fourier transform. Subsequently, we obtained the broad impedance spectrum of the measured object by merging odd-order harmonic spectral components up to the 19th order for each oscillation frequency. From the measured spectrum, the resistive and capacitive components of the circuit simulating bioimpedance were estimated with high accuracy. Moreover, the proposed method was used to measure the impedance of porcine myocardium; changes in the impedance spectrum of the myocardial tissue due to coagulation could be measured. Furthermore, rapid variations in the resistance value of a CdS photocell could be continuously measured using the proposed method.
format	article
author	Tomiharu Yamaguchi Emiyu Ogawa Akinori Ueno
author_facet	Tomiharu Yamaguchi Emiyu Ogawa Akinori Ueno
author_sort	Tomiharu Yamaguchi
title	Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement
title_short	Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement
title_full	Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement
title_fullStr	Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement
title_full_unstemmed	Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement
title_sort	short-time impedance spectroscopy using a mode-switching nonsinusoidal oscillator: applicability to biological tissues and continuous measurement
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/dce32157d747439a8e195c48adcd00fb
work_keys_str_mv	AT tomiharuyamaguchi shorttimeimpedancespectroscopyusingamodeswitchingnonsinusoidaloscillatorapplicabilitytobiologicaltissuesandcontinuousmeasurement AT emiyuogawa shorttimeimpedancespectroscopyusingamodeswitchingnonsinusoidaloscillatorapplicabilitytobiologicaltissuesandcontinuousmeasurement AT akinoriueno shorttimeimpedancespectroscopyusingamodeswitchingnonsinusoidaloscillatorapplicabilitytobiologicaltissuesandcontinuousmeasurement
_version_	1718431675249065984

Short-Time Impedance Spectroscopy Using a Mode-Switching Nonsinusoidal Oscillator: Applicability to Biological Tissues and Continuous Measurement

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