Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)

The new coronavirus infection (SARS-CoV-2), better known as COVID-19, quickly evolved into a worldwide pandemic with a significant public health burden. Currently, there are no approved drugs or preventive therapeutic strategies to combat infection. Decisions about prescribing many medications are m...

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Autores principales: Ya. E. Shirobokov, E. P. Gladunova, E. A. Borodulina, A. E. Sukhanova
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2021
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Acceso en línea:https://doaj.org/article/dceaf9e786774c56b29d74e5a0179e88
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spelling oai:doaj.org-article:dceaf9e786774c56b29d74e5a0179e882021-11-23T06:14:46ZOverview of potential drugs for the treatment of new coronavirus Infection (COVID-19)2541-94202587-959610.29413/ABS.2021-6.4.7https://doaj.org/article/dceaf9e786774c56b29d74e5a0179e882021-10-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2975https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The new coronavirus infection (SARS-CoV-2), better known as COVID-19, quickly evolved into a worldwide pandemic with a significant public health burden. Currently, there are no approved drugs or preventive therapeutic strategies to combat infection. Decisions about prescribing many medications are made based on the results obtained in in vitro studies, or expert opinions. Most of the drugs currently used to treat COVID-19 are approved antivirals or antibodies against other diseases. However, there are hundreds of clinical studies underway around the world to discover effective treatments for COVID-19. This article summarizes the results of clinical studies of potential therapeutic drugs used as COVID-19 therapy. Based on this review, it can be concluded that there is still no high-quality evidence to support any of the drugs described below. Until the unambiguous results of randomized controlled trials are available, the use of any of the following drugs is not clinically proven as an effective treatment for COVID-19.Ya. E. ShirobokovE. P. GladunovaE. A. BorodulinaA. E. SukhanovaScientific Сentre for Family Health and Human Reproduction Problemsarticlecovid-19sars-cov-2systematic reviewrandomized controlled trialScienceQRUActa Biomedica Scientifica, Vol 6, Iss 4, Pp 74-86 (2021)
institution DOAJ
collection DOAJ
language RU
topic covid-19
sars-cov-2
systematic review
randomized controlled trial
Science
Q
spellingShingle covid-19
sars-cov-2
systematic review
randomized controlled trial
Science
Q
Ya. E. Shirobokov
E. P. Gladunova
E. A. Borodulina
A. E. Sukhanova
Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)
description The new coronavirus infection (SARS-CoV-2), better known as COVID-19, quickly evolved into a worldwide pandemic with a significant public health burden. Currently, there are no approved drugs or preventive therapeutic strategies to combat infection. Decisions about prescribing many medications are made based on the results obtained in in vitro studies, or expert opinions. Most of the drugs currently used to treat COVID-19 are approved antivirals or antibodies against other diseases. However, there are hundreds of clinical studies underway around the world to discover effective treatments for COVID-19. This article summarizes the results of clinical studies of potential therapeutic drugs used as COVID-19 therapy. Based on this review, it can be concluded that there is still no high-quality evidence to support any of the drugs described below. Until the unambiguous results of randomized controlled trials are available, the use of any of the following drugs is not clinically proven as an effective treatment for COVID-19.
format article
author Ya. E. Shirobokov
E. P. Gladunova
E. A. Borodulina
A. E. Sukhanova
author_facet Ya. E. Shirobokov
E. P. Gladunova
E. A. Borodulina
A. E. Sukhanova
author_sort Ya. E. Shirobokov
title Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)
title_short Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)
title_full Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)
title_fullStr Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)
title_full_unstemmed Overview of potential drugs for the treatment of new coronavirus Infection (COVID-19)
title_sort overview of potential drugs for the treatment of new coronavirus infection (covid-19)
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2021
url https://doaj.org/article/dceaf9e786774c56b29d74e5a0179e88
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AT epgladunova overviewofpotentialdrugsforthetreatmentofnewcoronavirusinfectioncovid19
AT eaborodulina overviewofpotentialdrugsforthetreatmentofnewcoronavirusinfectioncovid19
AT aesukhanova overviewofpotentialdrugsforthetreatmentofnewcoronavirusinfectioncovid19
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