Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

Gene therapy (GT) using haematopoietic stem cells (HSCs) provides an opportunity to trace cell fates in humans, in vivo. Here the authors present evidence in GT patients for a long term lymphoid progenitor population, surviving and maintaining de novo T and NK cell production for years, independentl...

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Autores principales: Natalia Izotova, Christine Rivat, Cristina Baricordi, Elena Blanco, Danilo Pellin, Eleanor Watt, Athina S. Gkazi, Stuart Adams, Kimberly Gilmour, Jinhua Bayford, Claire Booth, H. Bobby Gaspar, Adrian J. Thrasher, Luca Biasco
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/dced9d3e9d5c441eaba1bc9789351905
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